Computational Scientist Jobs

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Senior Computational Research Scientist

St. Jude Children's Research Hospital•Memphis, TN

About The Position

The Senior Computational Research Scientist leads, performs, and develops computational research projects under minimal supervision. The role is with the Luber Lab in the Department of Radiology, which develops agentic workflows and foundation models at hospital-system scale. The research aims to identify algorithmic interventions and target trials that reduce excess mortality with the lowest possible implementation overhead by ingesting electronic health record (EHR), imaging, and omics data. The position requires expertise in computational research methods and the ability to apply advanced statistical modeling, machine learning, coding, software maintenance, computational pipelines, and data visualization to research goals. The scientist interprets and assesses data and results, develops methods, communicates findings to varied audiences, contributes to publications, and trains and oversees others. The role calls for independent work on complex problems, collaboration with stakeholders, and adapting to changing research needs.

Requirements

  • Bachelor's degree in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or a related field.
  • At least 7 years of relevant experience with a bachelor's degree; alternatively, at least 5 years with a master's degree or at least 2 years with a PhD.
  • Prior experience in computational research techniques and processes.
  • Proven performance in an earlier or comparable role.
  • Ability to think critically, draw insights, connect information, and make meaningful conclusions from data.
  • Ability to work with limited guidance, solve complex problems independently, and apply computational research procedures to defined outcomes.
  • Knowledge of the scientific domain and its informatics subdomain, including the ability to translate between scientific and engineering domains.
  • Ability to use advanced statistical modeling, machine learning, coding, software maintenance, computational pipelines, and data visualization.
  • Ability to interpret research requirements and independently execute relevant procedures, including handling process and quality escalations in one's area.
  • Ability to communicate complex ideas and research findings clearly to diverse audiences and stakeholders, and to tailor presentations to the audience.
  • Ability to prioritize data for presentations and publications and draft portions of these documents.
  • Technical and scientific expertise in experiment design and issue identification, and ability to apply research expertise strategically and practically.
  • Ability to adapt to change, recover from setbacks, anticipate roadblocks, and take corrective action based on data.
  • Ability to work effectively with partners and stakeholders to find solutions aligned with functional priorities.

Nice To Haves

  • Master's degree or PhD.
  • Publication record of 1–2 first-author papers with an impact factor above 10, or equivalent contributions to other research outputs.
  • Continued growth in domain knowledge through scientific journals, talks, and conferences.

Responsibilities

  • Lead computationally focused scientific research projects with minimal supervision from the principal investigator.
  • Develop new computational methods.
  • Identify, process, organize, interpret, review, and report relevant data.
  • Direct data collection.
  • Present research to colleagues within and outside the institution.
  • Draft complex manuscripts with minimal supervision, as required.
  • Regularly train and oversee others in computational research and procedures.
  • Perform other duties as assigned to meet department and institutional goals and objectives.
  • Maintain regular and predictable attendance.

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Based on current job postings on Teal, the average Computational Scientist salary in the US is approximately $108,000 per year, with a typical range of $52,000 to $200,000.
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