Principal Scientist, Integrated Computational and Experimental Inflammation Discovery
About The Position
The Principal Scientist will combine experimental and computational strategies to accelerate the discovery and development of innovative inflammation therapies. The role calls for deep expertise in wet-lab biology and AI/ML-driven computational and agentic research approaches to support human-data-driven understanding of disease mechanisms and therapeutic opportunities. The scientist will generate mechanistic insights, refine therapeutic hypotheses, guide experimental design, produce data supporting inflammation research programs, and contribute scientific recommendations to teams and governance forums.
Requirements
- Doctorate degree (PhD), or PharmD, or MD with relevant postdoctoral experience where applicable, and 2 years of industry experience in inflammation/immunology research.
- Alternatively, a master’s degree and 5 years of industry experience in inflammation/immunology research.
- Alternatively, a bachelor’s degree and 7 years of industry experience in inflammation/immunology research.
Nice To Haves
- Experience working effectively within highly collaborative and matrixed research environments.
- Ability to balance scientific rigor with urgency and adaptability in a dynamic research environment.
- Demonstrated commitment to teamwork, knowledge sharing, and continuous improvement.
Responsibilities
- Apply computational, agentic, and other AI-driven approaches to generate mechanistic insights, refine therapeutic hypotheses, and guide experimental design.
- Design, execute, analyze, and interpret studies investigating disease mechanisms and testing therapeutic hypotheses.
- Generate high-quality experimental data to support target identification, validation, and progression of inflammation research programs.
- Integrate experimental findings with published literature, human genetics, clinical observations, and other data sources to develop mechanistic insights and inform scientific decisions.
- Contribute data-driven insights and recommendations in scientific discussions, target reviews, and portfolio evaluations.
- Present scientific findings and recommendations to project teams, governance forums, and departmental meetings.
- Maintain accurate documentation and contribute to organizational knowledge-sharing efforts.
- Contribute to a culture of scientific curiosity, collaboration, continuous learning, and operational excellence.
Benefits
- Health and welfare plans for staff and eligible dependents
- Retirement and Savings Plan with generous company contributions
- Medical, dental, and vision coverage
- Life and disability insurance
- Flexible spending accounts
- Discretionary annual bonus program, or a sales-based incentive plan for field sales representatives
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible
- Career development opportunities
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What This Job Offers
Job Type
Full-time
Career Level
Principal
Education Level
Ph.D. or professional degree
