Director Jobs

About The Position

Requirements

• Doctoral degree (MD, PhD, MBBS or PharmD) or equivalent education
• 3+ years of demonstrated experience or strong expertise in Pulmonary Medicine, respiratory pharmacology, or immune mediated disease.
• Experience in late-phase clinical development and/or post-approval medical affairs.
• Well-developed comprehension of the US regulatory environment, including FDA and OPDP.
• Excellent scientific communication, presentation, and customer engagement skills.
• Ability to travel 20-25% on average within the US and occasionally internationally.

Nice To Haves

• Board certification or eligibility in Pulmonary or Internal Medicine.
• Strong biologics and new product launch experience
• Prior US pharmaceutical medical affairs experience, preferably in respiratory or biologics.
• Experience supporting first in class, disease modifying, or specialty launches.
• Strong understanding of the US payer and provider landscape.
• Demonstrated success in cross functional leadership and launch execution.

Responsibilities

• Serve as the US medical lead for COPD Biologics, accountable for development and execution of the US Brand Medical Plan across pre and post approval stages.
• Provide strategic medical input to US brand and launch strategy, ensuring alignment of scientific priorities with patient and clinical needs.
• Translate complex biology, clinical data, and disease state insights into actionable US medical strategies.
• Lead US medical strategy for late stage clinical development, including US input into Phase 3/3b study design, endpoint relevance to US clinical practice, subpopulation, and biomarker strategy.
• Support US regulatory readiness through medical review, scientific positioning, and collaboration with regulatory and global partners.
• Develop and implement pre-approval external scientific engagement strategy consistent with regulations, including scientific exchange on disease biology and unmet need and advisory boards focused on clinical trial interpretation and future treatment paradigms.
• Contribute to launch readiness planning, including medical education strategy, scientific platform development, and medical training for Field Medical teams.
• Partner with evidence, payer, and outcomes teams to define early value evidence strategy relevant to the US healthcare environment.
• Lead ongoing post-approval medical strategy to support appropriate scientific exchange and optimize patient care.
• Lead all aspects of Phase 4 and lifecycle management strategy, including real-world evidence (RWE) and effectiveness studies relevant to US clinicians and payers.
• Provide medical leadership for US publication strategy and congress planning, medical review of promotional and non-promotional materials, and scientific response strategy and data dissemination.
• Serve as a medical spokesperson for the US brand as appropriate, supporting external scientific discussions and media inquiries.
• Maintain accountability for the evolving US product scientific narrative, incorporating new data, guidelines, and real-world insights.
• Design and implement a comprehensive US external engagement plan, including Key Opinion Leaders (KOLs), academic institutions, integrated delivery networks and hospital systems, and professional societies.
• Lead planning and participation in national and regional US medical advisory boards.
• Ensure high-quality, compliant scientific exchange that advances understanding of COPD pathophysiology.
• Collaborate with medical evidence and payer teams to design and implement clinical effectiveness studies, RWE, and health outcomes research.
• Provide medical review and governance for Externally Sponsored Research (ESR) proposals.
• Provide medical input into product safety strategy in collaboration with Patient Safety colleagues.
• Ensure compliance with all US regulatory requirements, OPDP standards, PhRMA Code, and AstraZeneca policies.
• Provide clinical education and scientific training for US Field Medical organization and cross-functional partners (commercial, market access, HEOR).
• Act as a trusted US medical advisor to internal team members on COPD disease strategy and emerging science.
• Maintain strong collaboration with global medical and clinical teams, ensuring seamless alignment while representing US medical needs.

Benefits

• Qualified retirement program [401(k) plan]
• Paid vacation and holidays
• Paid leaves
• Health benefits including medical, prescription drug, dental, and vision coverage
• Short-term incentive bonus opportunity
• Eligibility to participate in our equity-based long-term incentive program (salaried roles)