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Senior Associate Scientist LNP Analytical Testing - Cambridge MA

VetJobs•Cambridge, MA
•$86,510 - $104,833•Onsite

About The Position

The Senior Associate Scientist performs analytical testing in support of research, process development, stability, and quality control activities. The role involves running assays such as ELISA and HPLC, executing and documenting experiments under SOPs, protocols, and GLP standards, and accurately analyzing and communicating experimental results. The scientist also maintains laboratory equipment, prepares reagents and standards, manages supplies, and supports analytical method development and optimization under the guidance of senior scientists. The role requires adherence to safety, EHS, and corporate policies and collaboration with colleagues across research, process development, and formulations. The position is based on-site in Cambridge, Massachusetts. The stated full-time salary range is $86,510–$104,833. Employees may also be eligible for discretionary cash incentives and stock opportunities.

Requirements

  • Bachelor's degree in Biochemistry, Chemistry, Biology, Pharmaceutical Sciences, or a related scientific discipline.
  • 1–5 years of hands-on laboratory experience; experience with RNA and/or lipid nanoparticles (LNPs) is preferred.
  • Proficiency with HPLC operations, including method execution, column management, and chromatography data systems.
  • Ability to manage multiple priorities in a fast-paced environment while maintaining accuracy and attention to detail.
  • Ability to analyze data and present results to the team and the broader research community.

Nice To Haves

  • Experience with RNA and/or LNPs, including academic research, internships, or industry roles.
  • Proficiency with ELISA, Western blotting, cell-based assays, UV-Vis spectroscopy, or qPCR.
  • Familiarity with chromatography data systems such as Empower, OpenLabs, or Chromeleon.
  • Experience or familiarity with mass spectrometry.
  • Familiarity with RNA characterization techniques such as SEC, CE, RT-PCR, or RNAseq.
  • Familiarity with ICH guidelines, GLP/GMP principles, and regulatory submission requirements.
  • Experience with LIMS and Benchling.
  • Experience with bioanalytical method validation, such as validation under FDA or EMA guidelines.
  • Working knowledge of statistical analysis tools such as GraphPad Prism, JMP, or Excel-based analysis.

Responsibilities

  • Perform routine analytical assays, including ELISA, HPLC, and other analytical methods, supporting research, process development, stability, and quality control activities.
  • Execute and document laboratory experiments according to established SOPs, protocols, and Good Laboratory Practice (GLP) standards.
  • Analyze, interpret, and summarize experimental data, and prepare clear and concise laboratory reports and technical summaries.
  • Maintain laboratory equipment through calibration and troubleshooting, and coordinate preventive maintenance with vendors.
  • Prepare reagents, buffers, and standards for analytical testing and manage laboratory consumables and supplies inventory.
  • Support method development and optimization under the guidance of senior scientists.
  • Comply with safety regulations, environmental health and safety (EHS) guidelines, and company policies.
  • Collaborate with colleagues in research, process development, and formulations.

Benefits

  • Potential eligibility for additional discretionary incentive cash and stock opportunities.

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