Lab Associate Jobs

437 jobs found — updated daily

Post Doctoral Associate- Dr. Amantha Thathiah Lab

University of Pittsburgh•Pittsburgh, PA
•Onsite
Match Resume

About The Position

The Thathiah Lab in the Department of Neurobiology at the University of Pittsburgh School of Medicine is recruiting two highly motivated postdoctoral associates to investigate the molecular and cellular mechanisms involved in Alzheimer's disease (AD) progression. Our lab studies AD mechanisms across molecular, cellular, and systems levels using human-derived induced neurons (iNs), glial models, and pre-clinical murine models. We integrate novel technologies to address hypothesis-driven questions in AD pathophysiology and advance the discovery of new therapeutic approaches. We seek individuals passionate about neuroscience and translational disease research who want to work in a collaborative, innovative environment and contribute to cutting-edge research with direct implications for AD therapies. Neuroimmune Communication in Alzheimer's Disease. The first postdoctoral associate will lead an exciting, NIH-funded project investigating the role of neuroimmune signaling in AD. Specifically, the focus will be on our recent discovery of the G protein-coupled receptor (GPCR), GPR3, which is highly expressed in glial cells and may activate neuroprotective responses to AD pathology. This position offers the opportunity to study how neuroimmune interactions modulate disease progression in AD. Mechanisms of Tau Pathobiology in Alzheimer's Disease and Other Tauopathies. The second postdoctoral associate will spearhead an ongoing project to investigate the molecular mechanisms underlying pathological tau phosphorylation and aggregation. The lab has recently developed an optogenetic model of tau aggregation (optoTAU) that provides a unique platform for exploring tau aggregation across multiple cell types, including neurons, astrocytes, and oligodendrocytes. This project will focus on the cellular and molecular modifiers and the consequences of tau aggregation to better understand its role in AD pathogenesis.

Requirements

  • A recent Ph.D. in neuroscience, biology, biochemistry, or a related field with a strong publication record
  • Expertise in sterile tissue culture techniques (required)
  • Proficiency with molecular biology techniques (e.g., RNA isolation and cloning)
  • Experience with biochemical approaches (e.g., protein isolation and Western blot analysis)
  • Experience with confocal microscopy (required)
  • Excellent verbal and written communication skills, technical expertise, and scientific creativity are essential.

Nice To Haves

  • Experience with IPSC reprogramming and disease modeling (preferred)
  • Experience with immunocytochemistry and immunohistochemistry (preferred)
  • Experience with single-cell, whole-genome, and proteomic analysis (preferred)
  • Experience with mouse handling, including injection, dissection, and behavioral approaches (preferred)

Responsibilities

  • Investigate the molecular and cellular mechanisms involved in Alzheimer's disease (AD) progression.
  • Study AD mechanisms across molecular, cellular, and systems levels using human-derived induced neurons (iNs), glial models, and pre-clinical murine models.
  • Integrate novel technologies to address hypothesis-driven questions in AD pathophysiology and advance the discovery of new therapeutic approaches.
  • Lead an NIH-funded project investigating the role of neuroimmune signaling in AD, focusing on the G protein-coupled receptor (GPCR), GPR3.
  • Study how neuroimmune interactions modulate disease progression in AD.
  • Investigate the molecular mechanisms underlying pathological tau phosphorylation and aggregation.
  • Explore tau aggregation across multiple cell types, including neurons, astrocytes, and oligodendrocytes.
  • Focus on the cellular and molecular modifiers and the consequences of tau aggregation to better understand its role in AD pathogenesis.

Benefits

  • Mentorship and strong support for applying for individual fellowships (e.g., NIH T32/F32, K awards)
  • Opportunities for impactful manuscript writing
  • Opportunities for presenting at conferences
  • Opportunities for advancing your career

Stand Out From the Crowd

Upload your resume and get instant feedback on how well it matches this job.

Upload and Match Resume

What This Job Offers

Job Type

Full-time

Career Level

Mid Level

Education Level

Ph.D. or professional degree

Job Search Resources

Build a Resume for Lab Associate

The resume builder that gets results.

  • Get clear feedback so you look as qualified as you are
  • Align your resume with the job to get further in the process, faster
  • Take the guesswork out of resume writing
Explore the resume builder

Explore Related Job Searches

TaManagerDirectorCtoTechnicianAnalyst

Tools

Templates & Examples

Resources

Comparisons

Company

Over 4 Million Users
Free AI tools and resources to help you land your next job, faster
© 2026 Teal Labs, Inc
Privacy PolicyTerms of Service