Computational Biologist Jobs

About The Position

Requirements

• PhD preferred in Computational Biology, Bioinformatics, Genetics, Genomics, Systems Biology, Biostatistics, Biomedical Engineering, or a related scientific discipline; alternatively, a Master's degree with 2 or more years of relevant experience.
• Demonstrated success applying computational approaches to biological or biomedical problems.
• Experience independently conducting scientific or biological analyses and managing defined projects or analytical workstreams.
• Experience applying computational methods to scientific questions and delivering clear, data-driven conclusions and recommendations.
• Ability to work effectively with limited oversight and seek guidance when needed.
• Working or strong proficiency in R and/or Python, or equivalent computational tools.
• Proficiency in statistical analysis, data visualization, reproducible research practices, and biological data analysis.
• Machine learning fundamentals.
• Demonstrated experience in at least one major scientific data domain, such as multi-omics, single-cell biology, spatial biology, genetics and genomics, imaging, clinical data, or real-world data.
• Strong intellectual curiosity, analytical rigor, attention to detail, and a growth mindset.
• Willingness to learn new biological domains, incorporate feedback, and partner with scientists and stakeholders.
• Permanent work authorization in the United States; U.S. work visa sponsorship is unavailable.
• Must live within commuting distance of a Pfizer location and work on-site an average of 2.5 days per week.

Nice To Haves

• Experience integrating multiple data sources.
• Experience in biotechnology, pharmaceuticals, healthcare, or biomedical research.
• Experience supporting drug discovery or development activities.
• Familiarity with AI-enabled scientific workflows.
• Experience working on multidisciplinary scientific teams.
• Exposure to translational, clinical, or therapeutic-area research.

Responsibilities

• Independently conduct defined analyses across biological, molecular, genetic, clinical, and translational datasets.
• Investigate scientific questions, generate hypotheses, identify meaningful biological patterns, and summarize findings clearly and rigorously.
• Deliver evidence-based insights that support scientific decision-making.
• Partner with computational biologists and scientific stakeholders to understand research challenges and analytical needs.
• Help define study populations, cohorts, labels, biological annotations, and evaluation criteria.
• Translate biological questions into executable computational workflows and learn how analytical choices affect scientific outcomes.
• Apply computational methods and statistical and computational best practices to generate high-quality scientific insights.
• Interpret results in biological and clinical context, assessing uncertainty, limitations, and alternative explanations.
• Build understanding of disease biology, clinical development, drug discovery, therapeutic-area decision-making, and stakeholder needs.
• Strengthen reproducible research practices and documentation standards.
• Communicate findings to scientific stakeholders and participate in multidisciplinary project discussions.
• Develop increasing independence in scientific problem-solving, stakeholder engagement, and influencing decisions through evidence.
• Contribute to analyses involving data types such as multi-omics, single-cell biology, spatial biology, genetics and genomics, imaging, perturbational biology, clinical trial datasets, and real-world data and evidence.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution.
• Paid vacation, holidays, and personal days.
• Paid caregiver, parental, and medical leave.
• Medical, prescription drug, dental, and vision coverage.
• Eligibility to participate in Pfizer’s Global Performance Plan, with a bonus target of 15% of base salary.
• Eligibility to participate in a share-based long-term incentive program.
• Relocation assistance may be available based on business needs and eligibility.
• Comprehensive benefits and programs intended to support colleagues’ health and life events.