Assay Development Scientist Jobs

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Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory

NovartisCambridge, MA
$152,600 - $283,400Onsite

About The Position

Imagine advancing biomarker science that helps transform promising discoveries into life-changing medicines. As a Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory, you will lead a high-performing team at the forefront of translational research, developing innovative biomarker assays that shape critical decisions across drug discovery and clinical development. Working across a diverse portfolio spanning renal, liver, fibrosis, and emerging disease areas, you will collaborate with leading scientists and cross-functional partners to accelerate patient-focused breakthroughs. This is an exciting opportunity to combine scientific leadership, strategic thinking, and innovation to make a meaningful impact on the future of medicine.

Requirements

  • Doctor of Philosophy, Medical Doctor, or equivalent degree in a relevant life sciences discipline.
  • Extensive experience developing biomarker assays within pharmaceutical or biotechnology environments.
  • Deep expertise across cellular, circulating, proteomic, genetic, and genomic biomarker approaches.
  • Proven success designing, qualifying, and implementing assays for preclinical and clinical studies.
  • Strong experience with platforms such as polymerase chain reaction, next-generation sequencing, immunoassays, and mass spectrometry.
  • Demonstrated ability to lead, develop, and inspire teams within complex matrix organizations.
  • Experience managing external partners and contract research organizations to deliver scientific outcomes.
  • Excellent collaboration, scientific communication, and stakeholder engagement skills.

Nice To Haves

  • Experience applying multiomics profiling and patient stratification approaches within translational research programs.
  • Strong strategic mindset with a track record of innovation and advancing scientific impact.

Responsibilities

  • Lead development and qualification of biomarker assays supporting discovery, translational research, and clinical development.
  • Design fit-for-purpose assay strategies enabling target engagement, pharmacodynamics, and patient stratification decisions.
  • Drive laboratory operations, resource planning, and prioritization to support portfolio objectives effectively.
  • Build, mentor, and develop a high-performing team of innovative biomarker scientists.
  • Foster a culture of scientific excellence, accountability, collaboration, and continuous improvement.
  • Partner with Translational Medicine, Data Science, and cross-functional project teams on biomarker strategies.
  • Establish and manage external collaborations to access emerging technologies and specialized scientific capabilities.
  • Oversee outsourced assay activities and ensure delivery of high-quality translational data.
  • Provide scientific leadership that informs translational plans and clinical development strategies.
  • Represent the laboratory in cross-functional forums and contribute to strategic program decisions.

Benefits

  • insurance plans
  • retirement plans
  • wellbeing resources
  • global recognition programs
  • flexible and hybrid working options
  • 14 weeks paid parental leave

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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Based on current job postings on Teal, the average Assay Development Scientist salary in the US is approximately $95,000 per year, with a typical range of $70,000 to $125,000.
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