Vice President of Sales, Oncology

BillionToOne

13h

About The Position

The Vice President of Oncology Sales owns BillionToOne’s commercial oncology sales function and leads a multi-layer field organization of nearly 100 representatives through Directors and Managers. The role sets sales strategy and operating cadence and is accountable for revenue, test volume, market share, and building a strong team. The position is part of the Executive Leadership Team and reports directly to the Chief Executive Officer. The Vice President partners with Marketing, Medical Affairs, Market Access and Reimbursement, Commercial Operations, Customer Experience, and Finance to translate clinical differentiation into sustainable commercial results. The role oversees sales execution for BillionToOne’s oncology portfolio, including Northstar®, a liquid biopsy test for comprehensive genomic profiling and treatment response monitoring. The location is flexible within the US. Travel is approximately 50%, including field work, cancer center visits, headquarters visits, and quarterly manager meetings.

Requirements

15+ years of sales experience in diagnostics, with deep, hands-on oncology diagnostics experience in areas such as molecular diagnostics, genomic profiling, liquid biopsy, or MRD/monitoring.
7+ years leading sales organizations, including Director-level leaders and a multi-layer field team.
Demonstrated record of exceeding revenue goals and growing market share in a competitive oncology diagnostics market.
Direct experience scaling a commercial team through a growth phase or major product launch.
Strong understanding of oncology buying dynamics, including medical oncologists, pathologists, practice administrators, health systems, and reimbursement’s role in adoption.
Proven ability to build, develop, and retain high-performing leaders through internal promotion and external recruiting.
Working fluency with sales operations, including territory design, incentive compensation, forecasting, CRM, and field analytics.
Bachelor’s degree.
Approximately 50% travel, including field work, cancer center visits, headquarters visits, and quarterly manager meetings.

Nice To Haves

No preferred qualifications are explicitly identified; leadership attributes include being an operator and builder, talent magnet, data-driven and candid, a cross-functional partner, resilient and urgent, and humble.

Responsibilities

Own the oncology revenue and volume plan, deliver annual and quarterly targets, and forecast accurately.
Lead, coach, and develop a multi-layer sales team, including Directors, Managers, Oncology Specialists, and specialty or account-based roles.
Design and refine territory structure, segmentation, targeting, and account coverage across community oncology, academic centers, integrated health systems, and key accounts.
Establish and operate a rigorous sales management system, including pipeline reviews, KPIs, call-plan and activity standards, performance management, and recognition programs.
Set hiring standards and lead talent strategy, including recruiting, onboarding, retaining talent, and building Director- and Manager-level succession.
Partner with Commercial Operations on incentive compensation, quotas, sales analytics, CRM, and field enablement.
Partner with Marketing and Medical Affairs on launch sequencing, messaging, KOL strategy, and clinical evidence supporting adoption.
Partner with Market Access and Revenue Cycle teams to improve payer coverage, reimbursement outcomes, and customer experience.
Build and maintain relationships with key opinion leaders, major cancer centers, health systems, and strategic accounts.
Monitor the liquid biopsy and MRD competitive landscape and turn market intelligence into effective commercial strategies.
Report market trends, competitive dynamics, and sales performance to senior leadership, and represent BillionToOne at oncology conferences, customer events, and advisory forums.

Benefits

Multiple medical benefit options, with employee premiums paid 100% for select plans and dependents covered up to 80%.
16 weeks of paid Family Bonding Leave at 100% for eligible employees.
Supplemental fertility benefits coverage.
Retirement savings program with a 4% company match.
Paid time off increases with tenure.
Base pay plus uncapped commissions.
Equity options.
Monthly car allowance.
Latest hardware, including a laptop, lab equipment, and facilities.
Free healthcare options are mentioned among company benefits.