Vice President of Sales, Oncology

BillionToOne

1d

About The Position

BillionToOne is seeking a Vice President of Oncology Sales to own its commercial oncology sales function and expand adoption of its oncology portfolio, including Northstar®, a liquid biopsy test for comprehensive genomic profiling and treatment response monitoring. The role leads a multi-layer field organization of nearly 100 representatives through Directors and Managers, sets sales strategy and operating cadence, and is accountable for revenue, test volume, market share, forecasting, and team quality.

The Vice President is a member of the Executive Leadership Team and reports directly to the Chief Executive Officer. The role partners with Marketing, Medical Affairs, Market Access and Reimbursement, Commercial Operations, Customer Experience, and Finance to translate clinical differentiation into durable commercial results. The position is flexible within the United States and requires approximately 50% travel, including field work, cancer center and headquarters visits, and quarterly manager meetings.

BillionToOne describes its culture as transparent, collaborative, empowering, and mission-driven, focused on making transformative molecular diagnostics accessible to patients. Compensation includes a base salary of up to $300,000 plus commission, equity, and a monthly car allowance.

Requirements

• 15+ years of sales experience in diagnostics, including deep, hands-on oncology diagnostics experience in molecular diagnostics, genomic profiling, liquid biopsy, or MRD/monitoring.
• 7+ years leading sales organizations, including Director-level leaders and a multi-layer field team.
• Demonstrated record of exceeding revenue goals and growing market share in a competitive oncology diagnostics market.
• Direct experience scaling a commercial team through a growth phase or major product launch.
• Strong understanding of oncology buying dynamics, including medical oncologists, pathologists, practice administrators, health systems, and reimbursement’s role in adoption.
• Proven ability to build, develop, and retain high-performing leaders through internal promotion and external recruiting.
• Working fluency in sales operations, including territory design, incentive compensation, forecasting, CRM, and field analytics.
• Bachelor’s degree.
• Approximately 50% travel, including field work, cancer center visits, headquarters visits, and quarterly manager meetings.

Nice To Haves

• Experience with oncology diagnostics involving molecular testing, genomic profiling, liquid biopsy, or MRD/monitoring.
• Experience scaling a commercial team during a growth phase or major product launch.
• Ability to operate strategically while managing the weekly rhythm of a large field organization.
• Industry reputation for attracting and developing sales representatives and leaders.
• Data-driven, candid, resilient, urgent, humble, and effective at cross-functional partnership.

Responsibilities

• Own the oncology revenue and volume plan; deliver annual and quarterly targets and forecast accurately.
• Lead, coach, and develop a multi-layer sales organization, including Directors, Managers, Oncology Specialists, and specialty or account-based roles.
• Design and refine territory structure, segmentation, targeting, and account coverage across community oncology, academic centers, integrated health systems, and key accounts.
• Establish and operate sales management practices, including pipeline reviews, KPIs, call-plan and activity standards, performance management, and recognition programs.
• Set hiring standards and lead talent strategy, including recruiting, onboarding, retaining talent, and building leadership succession at Director and Manager levels.
• Partner with Commercial Operations on incentive compensation, quotas, sales analytics, CRM, and field enablement.
• Partner with Marketing and Medical Affairs on launch sequencing, messaging, KOL strategy, and clinical evidence supporting adoption.
• Partner with Market Access and Revenue Cycle teams to improve payer coverage, reimbursement outcomes, and customer experience.
• Build and maintain relationships with key opinion leaders, major cancer centers, health systems, and strategic accounts.
• Track the liquid biopsy and MRD competitive landscape and use market intelligence to develop effective commercial strategies.
• Report market trends, competitive dynamics, and sales performance to senior leadership.
• Represent BillionToOne at oncology conferences, customer events, and advisory forums.

Benefits

• Multiple medical benefit options, with employee premiums paid 100% for select plans and dependent coverage up to 80%.
• 16 weeks of paid Family Bonding Leave at 100% for eligible employees.
• Supplemental fertility benefits coverage.
• Retirement savings program with a 4% company match.
• Paid time off increases with tenure.
• Latest hardware, including a laptop, lab equipment, and facilities.
• Base pay plus uncapped commissions, equity options, and a monthly car allowance.
• Company benefits include free healthcare options, a 401(k) match, and paid parental leave.
• Open, transparent culture with weekly Town Hall meetings.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive