Scientist/Senior Scientist, Translational Research (Pharmacological Sciences)

Voyager Therapeutics is seeking an experienced and motivated Scientist/Senior Scientist to join their Pharmacological Sciences team in Cambridge, Massachusetts. The successful candidate will contribute to the design and execution of various pharmacology and toxicology studies to support the development of novel capsids and biotherapeutics such as AAV-based gene therapy. They will work with cross-functional teams to execute in vivo pharmacology, biodistribution, PK/PD, and toxicology studies, perform quality control and analyze study data, and communicate study progress through presentations and written reports. This is a primarily on-site role with frequent travels to study sites.

• Contribute to experimental design, execution, and data analysis for preclinical studies
• Support development of novel capsids and biotherapeutics such as AAV-based gene therapy
• Interact with cross-functional capsid discovery and research program teams
• Execute in vivo pharmacology, biodistribution, PK/PD, and toxicology studies using AAV-based gene therapy approaches
• Perform quality control and analyze study data
• Communicate study progress through presentations and written reports
• Travel frequently to study sites.

• Strong background and hands-on experience in preclinical studies, including non-human primate (NHP)
• Experience in designing and executing pharmacology and toxicology studies to support development of novel capsids and biotherapeutics such as AAV-based gene therapy
• Ability to interact with cross-functional capsid discovery and research program teams to execute in vivo pharmacology, biodistribution, PK/PD, and toxicology studies using AAV-based gene therapy approaches
• Experience in quality control and analysis of study data, and communication of study progress through presentations and written reports
• Ability to serve as a study monitor to review study protocols and address requests/questions from external collaborators and CROs
• Coordination with capsid discover team, therapeutic program leads, and operations to set up studies aligned with project requirements and timelines
• Ability to monitor study progress and coordinate study activities, such as shipping and receiving of test article and tissue samples
• Willingness to travel and monitor in-life studies at CRO sites and report site-visit results to Voyager teams
• Ability to maintain and update key events in study log and database and timely communicate study status to program teams
• Experience in reviewing study reports, performing data analysis, and presenting study results as needed.