Scientist Jobs

About The Position

Requirements

• Bachelor's degree in a related field.
• Minimum of 5 years of laboratory experience handling and processing tumor specimens for single-cell analyses, flow cytometry, functional experiments, and immune assays.
• Highly collaborative, with the ability to multitask and work cross-functionally.
• Strong organizational skills and close attention to detail.
• Excellent written and verbal communication skills.

Nice To Haves

• Prior experience with molecular and cell biology techniques.

Responsibilities

• Coordinate acquisition, processing, annotation, and long-term storage of human tumor specimens, blood, lymph nodes, and matched normal tissues for cell therapy and translational research studies.
• Dissociate fresh tumor tissue using sterile mechanical and enzymatic methods to produce single-cell suspensions for immune profiling and cell manufacturing.
• Isolate, process, and cryopreserve tumor-infiltrating lymphocytes (TILs), peripheral blood mononuclear cells (PBMCs), tumor cells, and other primary cell populations while maximizing viability and recovery.
• Establish and maintain biobanking workflows, including sample tracking, chain-of-custody documentation, inventory management, and compliance with institutional, regulatory, and quality standards.
• Develop, optimize, and maintain patient-derived in vitro tumor models, including short-term cultures, organoids, tumor cell lines, spheroids, and autologous co-culture systems.
• Prepare biospecimens for single-cell sequencing, TCR repertoire analysis, transcriptomics, spatial profiling, proteomics, and genomic analyses supporting personalized TCR discovery workflows.
• Sort, enrich, and characterize immune and tumor populations using flow cytometry and magnetic bead-based technologies.
• Perform quality control assays to assess tissue viability, cell recovery, sterility, and sample integrity.
• Maintain laboratory records, electronic biobank databases, and standard operating procedures, ensuring compliance with biosafety, ethical, and regulatory requirements governing human biospecimens.
• Analyze experimental results, prepare summaries, and present findings at laboratory and project team meetings.
• Train laboratory personnel in tissue handling, biobanking procedures, aseptic techniques, and quality management practices.
• Conduct experiments with integrity and ethics and in accordance with laboratory, department, and college policies and procedures.