Scientist I, TCR-T Engineering and Translation

Weill Cornell Medical College•New York, NY

5d•$70,200 - $83,200•Onsite

About The Position

Supports the development of next-generation T cell receptor (TCR)-engineered T cell therapies by preparing engineered TCR-T cells and testing their biological properties. The role reports to the Assistant Lead and collaborates with the broader team to deliver IND-ready candidates for the clinic.

Requirements

Bachelor's degree in Biology, Biochemistry, or a related field.
Minimum of 8+ years of research experience in an academic laboratory or in the biotechnology or pharmaceutical industry.
Prior experience manipulating and culturing human T cells.
Prior experience in T cell engineering and molecular and cell biology techniques.
Prior experience conducting and analyzing adoptive T cell therapy studies using mouse tumor models.
Ability to collaborate, multitask, and work cross-functionally.
Strong organizational skills and close attention to detail.
Excellent written and verbal communication skills.

Responsibilities

Support IND-enabling preclinical studies for TCR-T cell programs.
Generate engineered TCR-transduced T cells using molecular and genomic technologies and platforms.
Perform cell-based functional assays to examine biological properties in vitro.
Assist in testing the potency of TCR-T cells in tumor models in vivo.
Analyze experimental data, prepare summaries, and present findings at team meetings.
Maintain accurate and detailed records of experimental methods and results in laboratory notebooks, and write SOPs.
As needed, assist in training researchers and laboratory staff in equipment use and experimental techniques.
Conduct experiments with integrity and ethics, following laboratory, department, and college policies and procedures.
Collaborate cross-functionally with teams including TCR discovery and vector development.
Stay current with literature and emerging technologies in the field.
Contribute to writing scientific posters and/or manuscripts.
Perform other related duties as assigned.