Sr. Associate Scientist

Pfizer • Bothell, WA

1d • $68,600 - $114,300 • Onsite

About The Position

A Senior Associate Scientist (R2) will join the Upstream Process Development group within Pfizer’s Bioprocess R&D organization. The group develops and optimizes manufacturing processes for recombinant proteins and other modalities for early- and late-phase human clinical trials. The scientist designs and executes laboratory experiments in bench-top bioreactors and associated scale-down equipment to develop robust, scalable, high-productivity processes.

The role also involves working with pilot, clinical, and commercial production facilities to support accurate technology transfer, successful large-scale production, and regulatory filing activities. The scientist may contribute to technology development projects that improve production processes and control strategies using process analytical technologies.

Requirements

• Bachelor’s degree with at least 3 years of industrial experience, or a Master’s degree with 0–2 years of experience, in Chemical or Biochemical Engineering, Cell Biology, Biotechnology, Biomedical Engineering, or a relevant field.
• Relevant research experience in a laboratory setting.
• Ability to grasp scientific concepts, interpret complex data, and formulate hypotheses.
• Competency in aseptic laboratory technique and ability to design and carry out complex experiments and interpret data.
• Demonstrated effectiveness in collaborative projects and ability to communicate effectively with scientists and management in a highly matrixed organization.
• Permanent work authorization in the United States; U.S. work visa sponsorship is not available.

Nice To Haves

• Hands-on experience with high-throughput bioreactor platforms, including ambr15 and ambr250 systems.
• Expertise in fed-batch or perfusion bioreactor operations, including process setup, control, troubleshooting, and scale-up of mammalian cell culture processes.
• Proficiency in process modeling and multivariate data analysis for process characterization and predictive process understanding.
• Experience with Python programming, workflow automation, or app development to create tools for experimental planning, data analysis, visualization, and knowledge-sharing.

Responsibilities

• Design and execute experiments in scale-down models, including shake flasks and bioreactors, to develop robust, high-yield, scalable manufacturing processes.
• Serve as the upstream technical lead and support accurate technology transfer to pilot and GMP manufacturing facilities.
• Provide technical support during manufacturing campaigns as needed.
• Document data accurately and promptly in electronic lab notebooks.
• Author technical reports and contribute to relevant sections of regulatory submissions, such as INDs and BLAs.
• Participate in lab and project team discussions on experimental design and data interpretation.
• Contribute to a safe, efficient, harmonious laboratory environment as a collaborative team member.
• Occasionally work weekends to passage flasks, sample bioreactors, or perform other essential tasks.

Benefits

• 401(k) plan with Pfizer matching contributions and an additional Pfizer Retirement Savings Contribution.
• Paid vacation, holidays, and personal days.
• Paid caregiver/parental and medical leave.
• Medical, prescription drug, dental, and vision coverage.
• Potential relocation assistance based on business needs and/or eligibility.
• Eligibility to participate in Pfizer’s Global Performance Plan, with a bonus target of 7.5% of base salary.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level