Sr. Associate Scientist

Pfizer • Bothell, WA

7d • Onsite

About The Position

A Senior Associate Scientist (R2) position is available in the Upstream Process Development group within Pfizer’s Bioprocess R&D organization. The successful applicant will join a team developing and optimizing manufacturing processes for recombinant proteins and other modalities for early- and late-phase human clinical trials. The role involves designing and executing laboratory experiments using benchtop bioreactors and associated scale-down equipment to develop robust, scalable, high-productivity processes. The scientist will work with pilot, clinical, and commercial production facilities to support accurate technology transfer, successful large-scale production, and regulatory filing activities. The role may also involve technology-development projects using process analytical technologies to improve production processes and control strategies.

The position is on premise. Occasional weekend work may be needed for essential tasks, and occasional travel may be required for internal meetings or external conferences. The annual base salary is $68,600 to $114,300, with eligibility for Pfizer’s Global Performance Plan and a 7.5% bonus target. Relocation assistance may be available based on business needs and eligibility. Candidates must have permanent U.S. work authorization; visa sponsorship is not available.

Requirements

• Bachelor’s degree and 2–4 years of industrial experience, or a master’s degree and 0–2 years of experience, in Chemical or Biochemical Engineering, Cell Biology, Biotechnology, Biomedical Engineering, or a relevant field.
• Relevant research experience in a laboratory setting.
• Ability to grasp scientific concepts, interpret complex data, and formulate hypotheses.
• Competency in aseptic laboratory technique and ability to design and carry out complex experiments and interpret data.
• Demonstrated effectiveness in collaborative projects and ability to communicate effectively with scientists and management in a highly matrixed organization.
• Permanent work authorization in the United States; U.S. work visa sponsorship is not available.

Nice To Haves

• Hands-on experience with high-throughput bioreactor platforms, including ambr15 and ambr250 systems.
• Expertise in fed-batch or perfusion bioreactor operations, including process setup, control, troubleshooting, and scale-up of mammalian cell culture processes.
• Proficiency in process modeling and multivariate data analysis for process characterization and predictive process understanding.
• Experience with Python programming, workflow automation, or app development to create tools for experimental planning, data analysis, visualization, and knowledge-sharing for process development scientists.

Responsibilities

• Design and execute experiments in scale-down models, such as shake flasks and bioreactors, to develop robust, high-yield, scalable manufacturing processes.
• Serve as upstream technical lead and ensure accurate technology transfer to pilot and GMP manufacturing facilities.
• Provide technical support during manufacturing campaigns as needed.
• Document data accurately and promptly in electronic lab notebooks.
• Author technical reports and contribute to relevant sections of regulatory submissions, including INDs and BLAs.
• Participate in lab and project team discussions about experimental design and data interpretation.
• Contribute to a safe, efficient, and harmonious laboratory environment as a collaborative team member.
• Occasionally work weekends to passage flasks, sample bioreactors, or perform other essential tasks.

Benefits

• 401(k) plan with Pfizer matching contributions and an additional Pfizer Retirement Savings Contribution.
• Paid vacation, holidays, and personal days.
• Paid caregiver/parental and medical leave.
• Medical, prescription drug, dental, and vision coverage.
• Eligible to participate in Pfizer’s Global Performance Plan, with a bonus target of 7.5% of base salary.
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level