Senior Vice President & General Manager, US Oncology

BioNTech•Berkeley Heights, NJ

21d•$362,800 - $446,600

About The Position

The Senior Vice President & General Manager, US Oncology will lead development and execution of the U.S. commercial strategy for BioNTech’s oncology portfolio. The role builds and leads a high-performing U.S. commercial organization, establishes the operating model to support current and future launches, and aligns commercial priorities with enterprise strategy, product development, market access, and launch readiness. Reporting to the Chief Commercial Officer, the General Manager is accountable for U.S. commercial performance, organizational development, budget management, and cross-functional collaboration. The role leads U.S. commercial strategy and execution, including launch planning and commercialization, market access, reimbursement and pricing strategies, and strategic relationships with external stakeholders. It also leads organizational growth, talent development, performance, and budget and resource decisions; coordinates with headquarters and U.S. functions; and supports appropriate commercial infrastructure in the New Jersey area. The role applies data, customer insights, and digital capabilities to improve commercial decisions and effectiveness, promotes responsible use of digital technologies including AI-enabled tools where appropriate, and monitors oncology and biopharmaceutical trends.

Requirements

Bachelor’s degree in a relevant discipline, such as business, life sciences, pharmacy, medicine, or a related field, or an equivalent combination of education, training, and relevant experience.
At least 15 years of experience in pharmaceutical or biotechnology commercial organizations.
At least 10 years of experience leading U.S. commercial strategy, marketing, sales, market access, launch, or general management activities.
Demonstrated experience successfully commercializing pharmaceutical or biotechnology products in the United States, including launch planning and execution.
Experience in oncology commercialization or another relevant specialty-care market.
Demonstrated ability to lead and develop teams, manage complex budgets, and make sound, data-informed business decisions.
Strong understanding of the U.S. healthcare ecosystem, including payer, provider, reimbursement, and access considerations.
Demonstrated ability to work effectively across functions and influence senior internal and external stakeholders.
Excellent communication, presentation, negotiation, and relationship-management skills.
Commitment to ethical conduct, patient focus, quality, and compliance with applicable laws, regulations, and company policies.

Nice To Haves

Advanced degree in business, medicine, pharmacy, life sciences, or a related discipline.
Experience building or scaling a U.S. commercial organization in a growth-stage, launch-focused, or rapidly evolving biopharmaceutical company.
Experience with personalized medicine, precision oncology, companion diagnostics, or complex biomarker-driven products.
Experience leading multiple product launches and/or supporting commercialization across multiple markets.
Experience implementing commercial-excellence capabilities, including analytics, digital engagement, and responsible application of AI-enabled tools.
Experience engaging with a broad range of U.S. healthcare stakeholders, including payers, provider organizations, healthcare professionals, and patient advocacy organizations.
Strategic thinking paired with strong execution discipline.
An entrepreneurial, pragmatic, and solutions-oriented approach.
Ability to move effectively between long-term strategy and near-term operational priorities.
Adaptability, resilience, sound judgment, and comfort leading through ambiguity and change.
A collaborative and inclusive leadership style that builds trust across diverse teams and stakeholders.
Strong personal integrity and a commitment to compliant, patient-centered commercialization.

Responsibilities

Develop, present, and execute a comprehensive U.S. commercial strategy aligned with anticipated product launches, market dynamics, and company objectives.
Define strategic objectives, initiatives, operating plans, milestones, and performance measures for the U.S. commercial organization.
Assess and adapt commercial plans in response to market conditions, customer insights, competitive activity, and portfolio evolution.
Lead U.S. launch planning and commercialization activities for oncology products in partnership with relevant internal functions.
Develop U.S. market access, reimbursement, and pricing strategies consistent with company strategy and applicable laws and policies.
Build and maintain compliant strategic relationships with healthcare professionals, patient advocacy organizations, payers, providers, and other relevant partners.
Build, scale, and lead the U.S. commercial organization, including organizational design, talent acquisition, capability building, succession planning, and performance development.
Establish a culture of accountability, collaboration, inclusion, ethical conduct, and high performance.
Lead through organizational growth and change, balancing strategic priorities with timely operational decisions.
Identify, develop, and retain diverse talent and create development opportunities across the organization.
Manage the U.S. commercial budget and contribute to P&L management, resource prioritization, and investment decisions.
Establish cross-functional governance and collaboration with headquarters and U.S.-based partners across R&D, Clinical Development, Medical Affairs, Regulatory, Market Access, Manufacturing, Finance, Legal, Compliance, HR, and Product Launch teams.
Ensure commercial perspectives and U.S. market insights inform product-development, launch, and lifecycle-planning decisions.
Foster organizational understanding of product profiles, development plans, and the U.S. oncology market.
Support establishment of appropriate U.S. commercial infrastructure, including evaluation of office and operational requirements in the New Jersey area, as applicable.
Apply data, customer insights, and digital capabilities to strengthen commercial decision-making and operational effectiveness.
Promote responsible use of digital technologies, including AI-enabled tools where appropriate, in alignment with company policies and applicable laws.
Monitor oncology, market access, commercialization, and broader biopharmaceutical trends to identify opportunities and risks.

Benefits

Medical, dental, and vision insurance
Life, AD&D, and critical illness insurance
Pre-tax HSA and FSA, and DCRA spending accounts
Employee Assistance & Concierge Program available 24/7
Parental and childbirth leave and family planning assistance
Virtual tutoring and childcare membership
Paid vacation, sick, bereavement, and holiday time, including floating holidays and year-end U.S. shutdown
401(k) plan with company match
Tuition reimbursement and student loan assistance programs
Wellbeing incentive platforms and incentives
Professional development programs
Commuting allowance and subsidized parking
Discounted home, auto, and pet insurance
Annual bonus and equity, variable and dependent on company and individual performance