Senior Associate Scientist, Pharmacology
About The Position
This laboratory-based role at RayzeBio advances radiopharmaceutical therapies through discovery research. The position conducts in vivo experiments and manages vivarium duties, including study design and execution, tissue collection, and data analysis. It collaborates with translational research, medicinal chemistry, and other scientific teams, receives mentorship from senior scientists, and requires strict adherence to radiation safety protocols. The role supports laboratory operations and compliance with company policies, GLP, IACUC, animal welfare guidelines, and radiation-safety requirements. The position may require work outside standard business hours, including weekends, holidays, and early mornings, to support critical studies and deadlines. It is based in a laboratory and vivarium environment involving radioactive and biohazard materials, with required protective clothing, gloves, and safety glasses.
Requirements
- B.Sc. with 3–4+ years of experience or M.Sc. with 1–2+ years of experience in Biology, Pharmacology, Translational Research, Molecular Biology, or a related discipline.
- Technical proficiency in rodent handling, including immune-compromised and immune-competent mice, aseptic procedures, and laboratory animal research.
- Ability to perform IV compound administration and SC engraftment.
- Working knowledge of MS 365 and GraphPad Prism.
- Strong work ethic, self-motivation, adaptability, and organizational skills.
- Ability to work in a fast-paced, dynamic, collaborative environment.
- Excellent written and oral communication and presentation skills.
- Familiarity with the drug development process and interdisciplinary teamwork.
- Ability to use AI tools to enhance individual productivity and quality of work.
Nice To Haves
- Hands-on experience in pre-clinical drug discovery programs in industrial or academic settings.
- Experience working with radioactive materials.
- Experience culturing and expanding cancerous cell lines.
- Experience with in vivo imaging modalities.
Responsibilities
- Design and conduct in vivo studies using CDX, PDX, and syngeneic mouse models to evaluate tumor growth kinetics, biodistribution, therapeutic efficacy, and durability of response across treatment modalities, including radiopharmaceutical agents.
- Perform cell culture, tumor cell and PDX fragment implantation, sampling, dosing by IV, SC, IP, and PO routes, tumor and body weight monitoring, and necropsy.
- Independently analyze and interpret experimental data and present findings at project team meetings, departmental reviews, and company-wide forums.
- Handle radioactive materials in compliance with institutional and federal radiation-safety protocols.
- Support laboratory operations, including inventory management and equipment maintenance.
- Comply with company policies, GLP, IACUC, and animal welfare guidelines, and accurately document work in laboratory notebooks and electronic records.
- Collaborate with the immediate team and cross-functional colleagues to advance program objectives.
- Troubleshoot experimental issues and ensure accurate data analysis.
- Work outside standard business hours, including weekends, holidays, and early mornings, when needed for critical in vivo studies and project deadlines.
Benefits
- Wellbeing support.
- Retirement and financial protection benefits.
- Medical, dental, vision, life, and disability insurance offerings.
- Flexible Time Off for eligible U.S.-based exempt employees, subject to manager approval.
- For non-exempt employees, RayzeBio employees, and employees located in Puerto Rico: 160 hours of paid vacation annually for new hires, subject to manager approval; 11 paid company holidays; and 3 optional holidays.
- Depending on eligibility, paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
- Eligible employees may receive an annual Global Shutdown between Christmas Day and New Year's Day.
- Potential eligibility for discretionary incentive cash and stock opportunities.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
