Senior Associate Scientist, Neuroscience, In Vitro Pharmacology

Bristol Myers Squibb • Cambridge Crossing, VA

7d • $105,040 - $127,287

About The Position

Bristol Myers Squibb is seeking a detail-oriented scientist to support high-throughput screening efforts within its neuroscience drug discovery organization. The role focuses on developing and executing scalable assays for compound and oligo screening campaigns to identify novel therapeutic targets and modulators. The scientist will work with cross-functional teams to advance screening pipelines and support therapeutic discovery.

Requirements

• Bachelor's degree in Biology, Neuroscience, Pharmacology, Biochemistry, or a related field and at least 4 years of relevant experience, or a Master's degree and at least 2 years of relevant experience.
• Experience in mammalian cell culture.
• Experience in assay development, compound screening, genetic perturbation, and troubleshooting at scale.
• Proficiency in cell viability and reporter assays, high-content imaging and analysis, and general molecular and cellular assay techniques.
• Experience with cell lines and other relevant in vitro systems.
• Ability to independently design, execute, troubleshoot, document, analyze, and present reproducible experiments.
• Strong organizational and communication skills, with the ability to work independently and cross-functionally in a fast-paced environment.
• Attention to detail, problem-solving skills, and commitment to scientific rigor, safety, and data quality.

Nice To Haves

• Familiarity with primary neuronal or iPSC-derived cultures.
• Strong data analysis or visualization skills.
• Familiarity with automation or robotics platforms and handling large datasets.
• Hands-on experience in an academic, biotechnology, or pharmaceutical setting.
• Curiosity, initiative, and adaptability.

Responsibilities

• Develop, optimize, and validate assays for high-throughput and high-content screening applications.
• Execute compound screening campaigns, including cell viability and reporter-based assays.
• Design and implement genetic perturbation screens, such as siRNA/ASO and CRISPR-based screens, to support therapeutic discovery.
• Perform high-content imaging and automated image analysis to extract quantitative phenotypic data.
• Maintain and scale mammalian cell culture systems, including cell lines and neuroscience-relevant in vitro models, to support screening throughput.
• Troubleshoot assay performance issues and implement process improvements to ensure data quality and reproducibility.
• Analyze large screening datasets, visualize results, and present findings to support go/no-go decisions.
• Document protocols and results in accordance with scientific and quality standards.
• Partner with automation, informatics, and target validation teams to advance screening pipelines.

Benefits

• Wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance offerings, subject to eligibility and plan terms.
• Flexible Time Off for eligible U.S.-based exempt employees, subject to manager approval.
• Paid vacation for eligible non-exempt employees, RayzeBio employees, and employees located in Puerto Rico.
• 11 paid company holidays; eligible employees in specified categories also receive 3 optional holidays.
• Depending on eligibility, paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Annual Global Shutdown between Christmas Day and New Year's Day for eligible employees.
• Potential eligibility for discretionary incentive cash and stock opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior