Scientist, NGS - Viral Delivery Technologies

Regeneron Pharmaceuticals • Tarrytown, GA

13d • $93,900 - $153,300 • Onsite

About The Position

Regeneron is seeking a Scientist to join its Viral Delivery Technologies group. The role supports development of a screening platform for antibody-retargeted adeno-associated virus (AAV) vectors. The Scientist will contribute to designing, characterizing, and validating novel AAV vectors in vitro and in vivo, helping expand the company's gene therapy delivery portfolio. The position involves collaboration with cross-functional team members, analytical groups, and core facilities across Research and Discovery in a fast-paced, collaborative environment.

Requirements

• B.A./B.S. with 8+ years of relevant industry or academic experience, or an M.S. in cell biology, molecular biology, biochemistry, bioengineering, antibody science, or a related field with 6+ years of relevant experience.
• Proficiency in next-generation sequencing (NGS), including library preparation, optimization, troubleshooting, and quality assessment.
• Strong molecular biology experience, including DNA isolation, PCR-based methods, and plasmid cloning.
• Experience in mammalian cell culture and manipulation, and in purification of viruses and/or proteins.
• Excellent presentation and communication skills.

Nice To Haves

• Familiarity with key antibody properties.
• Familiarity with viral vector production.
• Familiarity with relevant research software, such as Microsoft Office, GraphPad Prism, Benchling, and MacVector.

Responsibilities

• Design, execute, analyze, and troubleshoot in vitro and in vivo experiments to characterize and validate antibody-retargeted viral vector designs and screening protocols.
• Apply molecular biology and protein analysis techniques, including cloning, SDS-PAGE, Western blotting, DNA/RNA extraction, PCR, RT-PCR, digital droplet PCR, and qPCR.
• Design AAV genomes and execute recombinant AAV (rAAV) production protocols to inform novel vector optimizations.
• Develop, optimize, and troubleshoot next-generation sequencing (NGS) library preparation workflows for screening and characterization applications.
• Partner with the bioinformatics team to analyze large NGS datasets.
• Prepare regular updates and presentations for team and departmental forums.
• Work rigorously with close attention to detail while balancing multiple projects.

Benefits

• Annual bonuses or other incentive plans may be available, depending on country and role.
• Equity awards may be available, depending on country and role.
• Pension or retirement benefits may be available, depending on country and role.
• 401(k) company match may be available, depending on country and role.
• Health and wellness programs may be available, depending on country and role.
• Fitness centers may be available, depending on country and role.
• Insurance benefits, including medical, dental, vision, life, and disability insurance, may be available, depending on country and role.
• Paid time off may be available, depending on country and role.
• Family support benefits may be available, depending on country and role.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level