Director, Regional Access Team

Amylyx Pharmaceuticals•Cambridge, MA

12d•$245,000 - $265,000•Remote

About The Position

The Director, Regional Access will build, launch, and lead a high-performing Regional Access organization supporting timely and appropriate patient access to a potentially newly FDA-approved, self-injectable therapy for a rare endocrine disease. The role will develop launch-readiness plans, recruit and coach the regional team, establish operating standards, and connect with Payer National Accounts, Patient Services, Specialty Pharmacy, Sales, Commercial Operations, Training, Compliance, and other partners. The position requires deep expertise in pharmacy-benefit access, HCP office workflows, health-system business dynamics, specialty pharmacy operations, prior authorizations, step therapy, denials and appeals, payer policy, reimbursement education, patient support services, and regional and state Medicaid engagement. The Director will ensure that the Regional Access team helps patients, providers, and payer-facing stakeholders navigate access barriers in a compliant, patient-centered, and business-aligned manner. This is a remote-eligible, field-based leadership role within the United States, with customer engagement and field visits. It requires approximately 50% to 60% travel, including overnight travel by air and automobile, and several trips each year to the company’s Cambridge, Massachusetts location. The employee must be able to work effectively from a home office, customer sites, and other field locations, with appropriate privacy, reliable internet, phone, and video-conferencing access. The company is not currently considering applicants residing or working in Alaska, Arizona, Hawaii, Michigan, or Tennessee. The estimated pay range is $245,000–$265,000 USD. The final offer may vary based on experience, skills, qualifications, and internal equity.

Requirements

At least 10 years of pharmaceutical, biotech, market access, patient services, reimbursement, specialty pharmacy, or related commercial experience, including regional leadership.
Experience building, launching, scaling, and leading regional access, reimbursement, patient access, or market access teams in a complex specialty or rare disease environment.
Experience recruiting, onboarding, coaching, and developing high-performing regional teams and establishing clear expectations, operating rhythms, KPIs, and accountability measures.
Experience leading teams through product launch readiness, including developing deployment plans, access playbooks, training plans, and cross-functional launch-execution processes.
Deep knowledge of pharmacy-benefit access, specialty pharmacy, prior authorization, step therapy, denials and appeals, payer policy, HUB services, and HCP workflows.
Strong knowledge of regional payers, state Medicaid, IDN and health-system access pathways, institutional formulary processes, EMR workflows, and specialty pharmacy distribution models.
Track record of effective partnership across Market Access, Sales, Patient Services, Specialty Pharmacy, Trade, Commercial Operations, Medical, Legal, Compliance, Training, and Analytics.
Ability to translate complex payer, provider, specialty pharmacy, and patient journey insights into compliant regional strategies, operational improvements, and scalable national solutions.
Strong executive presence, communication skills, and business acumen, with the ability to influence senior leaders, cross-functional partners, and regional teams without authority.
Ability to work effectively from a home office, customer sites, and other field-based locations.
Ability to travel approximately 50% to 60%, including overnight travel by air and automobile, and to travel to Cambridge, Massachusetts several times a year and to other company events as requested.
Access to a remote work setting that supports privacy, reliable internet, phone service, and video conferencing.

Responsibilities

Build and execute the regional access launch-readiness plan for a rare disease endocrinology therapy using a pharmacy benefit and specialty pharmacy distribution model.
Define launch milestones, regional deployment plans, escalation pathways, access playbooks, and operating rhythms.
Define compliant regional launch activities, including account readiness planning, approved disease-state education, approved patient-support resource education where appropriate, and transition planning from launch preparation to post-approval execution.
Partner with Payer National Accounts, Trade, Patient Services, Brand, Sales, Medical, Legal, Compliance, Training, and Commercial Operations to align launch execution.
Translate payer coverage dynamics, specialty pharmacy requirements, prior authorization criteria, step edits, and patient affordability considerations into compliant regional strategies.
Recruit, onboard, coach, and develop a Regional Access team responsible for regional patient, provider, and payer access support.
Establish team roles, responsibilities, performance expectations, KPIs, and management processes.
Conduct regional rides, coaching sessions, business reviews, and performance assessments to promote consistent execution and continuous improvement.
Build a team culture grounded in the company’s stated values while reinforcing compliance, collaboration, urgency, and patient-centered problem solving.
Ensure compliant reimbursement and access education for HCPs, office staff, prior authorization teams, billing personnel, specialty pharmacy partners, providers, IDNs, COEs, health systems, and other access stakeholders.
Develop a national execution framework and equip the Regional Access team to educate customers, using approved materials, on payer requirements, prior authorizations and appeals, coding, pharmacy benefits, EMR and formulary workflows, distribution expectations, patient support resources, and health-system access considerations.
Guide the Regional Access team in identifying and escalating access barriers through approved channels, including coverage gaps, affordability challenges, payer policy changes, specialty pharmacy delays, distribution issues, HUB issues, and therapy-initiation delays.
Serve as a regional subject matter expert on specialty pharmacy and health-system workflows, limited distribution networks, payer-mandated pharmacies, shipment coordination, onboarding, refill continuity, pharmacy leadership, and treatment-initiation milestones.
Partner with Patient Services, Specialty Pharmacy, HUB Operations, Trade, and other stakeholders to improve enrollment quality, benefits investigation, prior authorization and copay support, coordinated handoffs, and patient continuity.
Establish compliant feedback loops to identify recurring regional and system-level barriers, determine root causes, escalate unresolved issues, share best practices, and turn effective approaches into scalable national playbooks.
Use appropriately aggregated, de-identified regional insights, patient journey trends, payer dynamics, and specialty pharmacy performance data—consistent with consent, privacy requirements, company policy, and approved data-use standards—to inform payer strategy, access materials, training, service-model enhancements, and operational improvements.
Represent Regional Access and provide market-access landscape education, regional insights, education, and strategic input in launch and brand planning, patient-services governance, sales leadership meetings, business reviews, QBRs, leadership forums, and cross-functional planning sessions.
Synthesize regional intelligence on payer barriers, provider workflow needs, specialty pharmacy performance, patient journey gaps, competitive access dynamics, and training opportunities.
Collaborate with Analytics and Operations to develop dashboards, KPIs, case trends, access metrics, and actionable business recommendations.
Partner with Training and Compliance to ensure regional execution meets company policies and regulatory expectations.
Ensure consistent cross-functional execution, market-access insight sharing, regional education, and timely escalation of access barriers across relevant teams and business forums.