Cheminformatics Analyst

Guidehouse•Rockville, MD

3d•Onsite

About The Position

Our federal client conducts chemical analyses to support rapid and precise regulatory decision-making. As a member of the Computational Toxicology Consultation Service team, this role involves leading clear, accurate communication of project consultation plans, findings, and results to internal stakeholders and external collaborators. The position requires establishing time estimates and resources for project execution and delivery schedules, acquiring and assembling data for interpretive reviews of chemical models and structures, and generating chemistry model predictions. A key responsibility is determining probable in-vitro toxicity, animal toxicity, or adverse human clinical effects. The analyst will manage 8-12 chemical batches weekly, including intake, execution, documentation, and delivery of results. This includes cataloging and recording experimental data in an appropriate format for sharing and publishing, detailing methods and procedures for reproducibility, summarizing and quality assuring data, and maintaining an archive of results in the department knowledge database. The role also focuses on improving the performance of chemistry models for future regulatory research project assessments and attending relevant applied regulatory science and drug innovation department meetings.

Requirements

Bachelor’s degree in chemistry or relevant area of study.
0-1 years of experience with data collection, analysis, and writing scientific manuscripts and technical reports.
Experience in organic chemistry, cheminformatics, and chemical drawing for regulatory research project assessments.
Provide analysis of toxicology evaluations and report results
Strong oral and written communication skills to engage with stakeholders.
Understanding of analysis results, targets, project plans and timelines.
Experience with chemical drawing tools and QSAR analyses.

Nice To Haves

Master’s degree in Chemistry or studies in pharmaceutical science and toxicology.
Experience with CASE Ultra, Leadscope Model Applier/Enterprise, and Derek/Sarah Nexus computational toxicology software.
Experience with public health agencies such as HHS, FDA, NIH and CDC.

Responsibilities

Lead clear, accurate communication of project's consultation plans, findings, and results to internal stakeholders and external collaborators at all levels.
Establish time estimates and resources required to execute project plans and delivery schedules.
Acquire and assemble data for interpretive reviews of chemical models, chemical structures and generate chemistry model predictions.
Determine the probable in-vitro toxicity, animal toxicity, or adverse human clinical effects.
Manage 8–12 chemical batches per week, including intake, execution, documentation, and delivery of results.
Catalog and record experimental data in an appropriate format to share and publish.
Record detailed methods and procedures of each activity, sufficient to allow for reproduction; summarize and quality assure data; Maintain an archive of results in department knowledge database.
Improve the performance of chemistry models for future regulatory research project assessments.
Attend relevant applied regulatory science and drug innovation department meeting.

Benefits

Medical, Rx, Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Parental Leave
401(k) Retirement Plan
Group Term Life and Travel Assistance
Voluntary Life and AD&D Insurance
Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
Transit and Parking Commuter Benefits
Short-Term & Long-Term Disability
Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
Employee Referral Program
Corporate Sponsored Events & Community Outreach
Care.com annual membership
Employee Assistance Program
Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)