Associate Scientist, Novel Oligonucleotide Delivery Platforms

Regeneron Pharmaceuticals • Tarrytown, GA

2d • $70,300 - $110,100 • Onsite

About The Position

We are seeking a highly motivated associate scientist to join the Non-Viral Delivery Technologies group within Regeneron Genetic Medicines. You will support production, purification, and characterization of proteins and larger macromolecular protein-based nanocarriers to be used in next-generation delivery technology development, further expanding the company’s growing genetic medicines portfolio.

Requirements

• A BS/MS in molecular biology, biochemistry, bioengineering, or related field
• Previous experience in cloning, bacterial-based expression systems, self-assembled VLPs are a plus.
• Experience with aseptic technique used in mammalian cell culture, chromatography, running an AKTA Pure, and SDS-PAGE/CE are distinct advantages.
• To be successful in this role, you need to work collaboratively, have attention to detail, and be organized.

Nice To Haves

• Enjoy working in a fast-paced environment with rapid hypothesis generation and testing
• Can troubleshoot through logistical and technical hurdles as they arise
• Can work independently and show initiative to continually improve protocols and processes
• Can tolerate failure, ambiguity, data-driven pivots on changing priorities and project direction

Responsibilities

• Maintenance and manipulation of bacterial and mammalian cells for protein expression
• Designing and cloning constructs into appropriate expression vectors
• Operation of AKTA systems for small scale purification by liquid chromatography-based techniques (e.g. affinity, ion exchange, size exclusion)
• In vitro reporter assays with adherent and suspension cell lines or primary cells
• Characterization of proteins (e.g. SDS-PAGE, SE-UPLC, CE, DLS)
• Working collaboratively with other team members and groups around the company

Benefits

• health and wellness programs (including medical, dental, vision, life, and disability insurance)
• fitness centers
• 401(k) company match
• family support benefits
• equity awards
• annual bonuses
• paid time off
• paid leaves (e.g., military and parental leave)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Associate degree