VP, Commercial Planning
About The Position
Alto Neuroscience is seeking an experienced Vice President, Commercial Planning to serve as its first fully dedicated commercial hire and help transition the company from a clinical-stage biotech to a launch-ready commercial organization. The role will establish the foundation for Alto’s commercial function, leading new product planning, commercial analytics and forecasting, launch readiness planning, early commercial strategy, and the infrastructure needed to support a future commercial organization. This is a hands-on, build-from-zero leadership role for someone who has built commercial capabilities in a pre-commercial or early-commercial biotech environment. The position is primarily internally focused, translating clinical, market, and competitive insights into commercial analyses, plans, and infrastructure to support executive decision-making and future commercialization. The Vice President will lead commercial strategy for ALTO-207 and new product planning for pipeline programs; build forecasting, market research, and analytics capabilities; and own cross-functional launch readiness planning. As the function grows, this leader will recruit and lead commercial analytics, commercial operations, and new product planning teams, and provide strategic direction to consultants, vendors, and cross-functional project teams. The position is preferred to be based in Mountain View, California, in a hybrid arrangement, though remote candidates may be considered. Light travel is required, with additional travel as business needs dictate.
Requirements
- At least 12 years of biotech or pharmaceutical commercial experience, including direct experience in new product planning, commercial analytics, forecasting, launch strategy, or related commercial functions.
- Demonstrated experience building commercial capabilities in a pre-commercial or early-commercial biotech environment, ideally as a first or early commercial hire.
- Strong forecasting, market sizing, and quantitative analytical skills, including the ability to personally develop and evaluate models and analyses.
- Experience developing commercial strategy and translating clinical, competitive, and market insights into actionable commercial plans.
- Experience building or scaling commercial analytics, market research, data infrastructure, and related commercial capabilities.
- Experience partnering cross-functionally with Clinical Development, Medical Affairs, Regulatory, and Market Access/HEOR on development and commercialization strategy.
- Demonstrated ability to build and lead teams while remaining hands-on in a lean, evolving organization.
- Strong written and verbal communication skills, including the ability to synthesize complex analyses into clear recommendations for executive leadership.
- Bachelor’s degree in business, life sciences, economics, finance, or a related field.
- Ability to travel as needed to support business requirements.
Nice To Haves
- CNS, psychiatry, or neurology therapeutic area experience.
- Direct experience supporting a CNS/psychiatry product launch.
- Prior small- or mid-cap public biotech experience.
- MBA or advanced scientific degree.
Responsibilities
- Lead commercial strategy for ALTO-207 and new product planning for pipeline programs, including market sizing, epidemiology-based patient flow modeling, target product profile input, and market opportunity assessment.
- Conduct competitive landscape and positioning analysis for TRD, adjunctive MDD, and bipolar depression markets to inform commercial strategies and launch plans.
- Partner with internal development teams so trial design, endpoints, and label strategy reflect commercial and market access realities.
- Build and maintain commercial forecasting capabilities, updating assumptions as clinical data, competition, and market insights develop.
- Design and execute primary and secondary market research to inform development plans, market opportunity, positioning, pricing, and launch assumptions.
- Establish commercial data and analytics infrastructure, including systems, partners, data sources, and reporting processes.
- Translate analytics and market insights into recommendations and decision-support materials for executive leadership.
- Serve as the internal commercial planning lead as Alto develops a broader commercial organization.
- Provide commercial input into protocol design, including dosing and titration strategy and label-relevant endpoints.
- Own the cross-functional launch readiness roadmap and coordinate key workstreams.
- Provide commercial input into portfolio prioritization and capital allocation discussions associated with key data readouts.
- Build and lead commercial analytics, commercial operations, and new product planning teams as the function scales.
- Select and implement foundational systems, including forecasting tools, data partners, market research vendors, and competitive intelligence platforms.
- Establish documentation, processes, and institutional knowledge that can scale with the commercial organization.
- Build the internal go-to-market strategic plan and supporting infrastructure for engagement with external stakeholders such as KOLs, advocacy groups, and investors.
- Equip internal partners and stakeholders with market sizing, competitive analysis, and positioning materials for KOL, advocacy, and investor conversations.
- Monitor the CNS/psychiatry competitive landscape, including comparable-mechanism launch performance, and prepare internal briefing materials.
- Recruit, develop, and lead Alto’s initial commercial analytics, commercial operations, and new product planning teams as headcount is approved.
- Provide strategic direction and oversight to consultants, vendors, and cross-functional project teams.
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What This Job Offers
Job Type
Full-time
Career Level
Executive
