Sr. Director, Portfolio Positioning & Communications

GondolaBio Service Co•Palo Alto, CA

About The Position

GondolaBio is a standalone rare disease innovator formed as a spin-out from BridgeBio, with independent governance, capital, and leadership. It develops therapeutics for diseases with genetically defined targets and has several clinical-stage programs across genetic specialties, neurology, and renal. Its purpose-built discovery and development engine uses biological research to create and deliver transformative medicines. The Sr. Director, Portfolio Positioning & Communications will own and refine GondolaBio’s corporate and portfolio narrative, develop scientifically grounded and commercially compelling value propositions for individual programs, and help shape markets for innovative or emerging treatments. The role translates complex scientific and market evidence into credible external narratives for investors, potential partners, and other sophisticated audiences. It works closely with program teams, Business Development, Corporate Strategy, and leadership, and directs specialist communications support as needed. The role also leads partner- and investor-facing materials, strategic content for conferences and company events, and message consistency across corporate channels. It applies AI and digital research tools to scientific and competitive synthesis and content workflows, with rigorous fact-checking, traceable sources, and appropriate confidentiality. GondolaBio describes its environment as decentralized, collaborative, fast-paced, and data-driven, with an emphasis on patient-first decisions, scientific integrity, ownership, and effective cross-functional work.

Requirements

Advanced scientific degree, such as a Ph.D., M.D., or PharmD, or equivalent scientific depth; strong strategic and commercial fluency is essential.
Approximately 8 or more years in biopharma portfolio or product strategy, new-product planning, life-sciences consulting, healthcare equity research, investor relations, strategic scientific communications, or related roles; demonstrated capability matters more than tenure.
Exceptional ability to understand complex biology and create clear, persuasive, differentiated narratives for sophisticated industry and investor audiences.
Demonstrated original strategic thinking about disease markets, product positioning, clinical-commercial evidence, and value creation, beyond presentation production.
Hands-on experience creating high-impact partner and investor materials and supporting senior executives in external interactions.
Ability to synthesize stakeholder and market insights and work effectively with scientific, commercial, and corporate teams.
Comfort using AI, digital research, and advanced content tools with strict scientific verification and appropriate confidentiality in a lean, fast-paced environment.
Commitment to patient-first work, ethical standards, clinical and scientific integrity, rigorous evidence-based decision-making, collaboration, and accountable execution.

Nice To Haves

Experience in rare and genetic diseases.
Experience in first-in-class product planning, new-market development, or category creation.
Exposure to equity research or corporate investor narratives and major biopharma conferences.
Relevant networks among investors, strategic partners, KOLs, or patient organizations.

Responsibilities

Own and continuously refine GondolaBio’s strategic and investment narrative, connecting its development model, therapeutic franchises, portfolio, and value-creation milestones.
Partner with program leaders to develop scientifically grounded, commercially compelling asset value propositions covering unmet need, genetics and biology, patient populations, clinical and regulatory path, competitive differentiation, commercial potential, and evidence gaps.
Help define opportunities for innovative or emerging programs through care pathways, stakeholder insights, evidence requirements, and market-development hypotheses.
Work with program teams to define stakeholder engagement along the patient journey.
Structure and synthesize insights from industry partners, investors, KOLs, and external market participants to refine positioning, test assumptions, and inform program and franchise strategies in accordance with scientific and compliance processes.
Lead corporate, franchise, and asset presentations, pitch decks, executive briefing materials, and other high-stakes partner- and investor-facing content.
Adapt investment-case materials to potential development partners and investors while maintaining scientific precision.
Define strategic themes and lead substantive content for priority conferences, including JPM, Jefferies, BIO, and disease-specific meetings, as well as curated GondolaBio events.
Steward message consistency across the website, targeted media, executive communications, digital channels, and external agencies; set editorial and strategic direction and leverage external specialist support.
Apply AI and digital tools to literature and competitor synthesis, message testing, scientific-content development, and efficient materials updates, with strong fact-checking, source traceability, and confidentiality practices.
Work closely with program teams, Business Development, Corporate Strategy, and leadership; use shared scientific and market evidence while owning narrative and positioning outputs, and contribute to cross-functional program and partnering forums.

Benefits

Patient Days to hear directly from people living with the conditions GondolaBio seeks to impact.
A values-inspired culture centered on putting patients first, independent thinking, radical transparency, urgency, and letting science speak.
A decentralized affiliate structure designed to reduce bureaucracy and place decision-making with teams closest to the science.
Ownership of the vision for programs and individual career paths.
A collaborative, fast-paced, data-driven environment.
Access to learning and development resources.
Market-competitive compensation and benefits, including base pay, performance bonus, equity, and health, welfare, and retirement programs.
Flexible PTO.
Potential for rapid career advancement for strong performers.
Potential to work on multiple GondolaBio Pharma programs across therapeutic areas over time.