Senior Scientist – Automation

Thermo Fisher Scientific•Collegeville, PA

3d•Onsite

About The Position

Thermo Fisher Scientific is hiring a Senior Scientist for its Analytical Services team, supporting a functional service provider partnership at a pharmaceutical or biopharmaceutical company. The role focuses on laboratory automation and analytical work that supports drug product development. The employee will use liquid-handling automation and analytical techniques to enable rapid screening and development, reduce design-selection risks, and address product-design issues across development phases. The position contributes to automation capabilities and workflows within the global automation organization.

Requirements

BS degree with 4 or more years of experience, MS degree with 2 or more years of experience, or PhD with 0–2 years of experience in an appropriate subject area.
Solid understanding of general biology, chemistry, and separation science.
Product-development experience across multiple projects in a pharmaceutical development environment, with evidence of achieving product deliverables within disciplinary expertise.
Broad knowledge of analytical method development supporting new chemical entity development.
Effective oral and written communication skills.
Proficiency operating automated liquid-handling systems, such as Hamilton systems.
Ability to troubleshoot and diagnose problems in analytical platforms.
Ability to collaborate with internal and external groups and work effectively in a matrix and team environment.
Learning agility and ability to work effectively in new situations or changing conditions.
Knowledge and experience with statistical design of experiments and analysis of results.
Ability to integrate, test, and troubleshoot analytical instrumentation.
Understanding of laboratory requirements, PPD and client SOPs, ICH guidelines, USP requirements, and FDA guidance.
Ability to use Microsoft Excel, PowerPoint, and Word to perform job tasks.
Proficiency with technical operating systems and technical writing.
Time-management and project-management skills.

Responsibilities

Conduct experiments using liquid-handling automation and appropriate analytical techniques, including surface plasmon resonance, capillary gel electrophoresis, and cell-based bioassays.
Apply automation assets for rapid screening and development to reduce design-selection risks and improve product design across development phases.
Troubleshoot laboratory errors and systematically assess root causes, including human, software, hardware, firmware, and chemical sources.
Organize, evaluate, and present data through discussions, presentations, and reports.
Contribute to developing new automation approaches and knowledge within the global automation organization.
Maintain local capability to rapidly demonstrate existing laboratory automation to address drug-development design-selection issues.
Write protocols for new automation workflows using robotic-specific software for laboratory instruments.