Senior Executive Assistant, Technology & National Security

Alloy Therapeutics•Waltham, MA
•$135,000 - $155,000•Hybrid

About The Position

Alloy Therapeutics is seeking a Senior Executive Assistant to support its Chief Technology Officer, who also serves as CEO of Alloy’s national security division, Vigilance. The role owns the CTO’s time and logistics, making informed calendar decisions, coordinating complex domestic and international travel, and serving as the polished and discreet point of contact for the Office of the CTO. The assistant partners closely with the VP, Business Operations to translate priorities into schedules, prepare meeting materials, and track follow-ups. The position supports leadership meetings, business reviews, quarterly planning, board preparation, offsites, retreats, partner meetings, and visiting delegations. It also includes managing expenses, vendors, and office budgets; helping new leaders get set up; and using modern productivity and AI tools to improve office operations. The work can involve changing plans, early mornings, occasional travel, and flexibility across time zones. The position is hybrid in Greater Boston, with primary working hours on U.S. Eastern time.

Requirements

  • Typically 8 or more years supporting C-suite executives or senior government officials.
  • Experience owning a senior executive’s calendar and making priority decisions on the executive’s behalf within agreed-upon bounds.
  • Experience orchestrating complex international travel across multiple time zones for a senior executive, including last-minute changes.
  • Experience handling confidential matters for senior executives and serving as a primary contact for board members, senior executives, or government officials.
  • Experience running preparation and follow-up systems that keep an executive ahead of commitments, with examples of anticipating issues.
  • Experience using modern calendar, email, document, and AI tools to automate or streamline an executive office.
  • A servant-leadership approach to supporting executives and teams, with examples of making leaders more effective.
  • Ability to flex working hours across time zones when the CTO is traveling and to travel occasionally for offsites and key events.
  • Include with the application a short note describing the most complex week orchestrated for an executive and one judgment call made on the executive’s behalf without being asked; applications without this note will not be considered.

Nice To Haves

  • Experience supporting executives in technology, biotechnology, or the public sector.
  • Familiarity with diplomatic or government protocol.

Responsibilities

  • Manage the CTO’s calendar with strategic judgment, prioritizing commitments, protecting focus and personal time, sequencing the week, and anticipating conflicts.
  • Plan and manage complex domestic and international travel, including multi-city itineraries, visas, time-zone transitions, and contingencies.
  • Triage correspondence and requests and represent the Office of the CTO with warmth, polish, and discretion to executives, board members, government officials, and partners.
  • Work with the VP, Business Operations to turn the CTO’s priorities into time and logistics, assemble briefing books and meeting materials, and track meeting follow-ups and action items through completion.
  • Coordinate logistics and preparation for weekly leadership meetings, monthly business reviews, quarterly planning sessions, and board preparation across U.S. and European time zones.
  • Plan leadership offsites, retreats, partner meetings, and visiting delegations, including venue and agenda logistics, protocol, and follow-through.
  • Manage expenses, vendors, and office budgets, and help new leaders get set up and connected.
  • Use modern productivity and AI tools to automate routine work and continuously improve office operations.

Benefits

  • 401(k) company match.
  • Medical, dental, and vision benefits with 100% of premiums and deductibles covered.
  • Company-paid short-term disability, long-term disability, and life insurance.
  • Paid parental leave.
  • Family planning support up to $45,000, including IVF/PGT, adoption, surrogacy, and egg retrieval.
  • Unlimited paid time off and flexible schedules.
  • Annual continuing-education stipend.
  • Individualized professional development plan.
  • Wellness resources and an extensive Employee Assistance Program, including mental wellness resources.
  • Equity compensation.
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