Senior Clinical Trial Associate

Immatics • Houston, TX

6d • $95,000 - $120,000 • Remote

About The Position

Immatics is seeking a highly organized and proactive Senior Clinical Trial Associate to join its Clinical Operations team. The role provides operational and administrative support to help ensure clinical trials are executed efficiently, compliantly, and to high quality standards. The position reports to the Associate Director, Team Lead Site Operations, and is fully remote in the United States. Optional business travel may be undertaken.

The Senior CTA supports clinical trial start-up, activation, maintenance, and closeout; essential study documentation and clinical systems; coordination with internal teams, CROs, vendors, and investigative sites; and audit and inspection readiness. The role also supports study financial tracking, site communications, training and access coordination, issue follow-up, process improvement, and development of study guidance and training materials. The stated salary range is $95,000 to $120,000.

Applicants must be authorized to work in the United States without current or future sponsorship. Employment is contingent on successful background and reference checks and, where permitted by law, pre-employment drug screening. Additional screenings may apply to certain roles.

Requirements

• Bachelor’s degree in life sciences, nursing, or a related field.
• At least 4 years of working experience in clinical research in the Pharmaceutical or Biotech industry, with ICH-GCP knowledge, or equivalent.
• Must be authorized to work in the United States without the need for current or future sponsorship.

Nice To Haves

• Strong problem-solving skills, including the ability to analyze issues, identify root causes, and implement effective solutions.
• Self-motivated and able to work independently in a fast-paced environment.
• Strong understanding of clinical trial processes and interconnected operational workflows.
• Continuous improvement mindset and interest in enhancing processes and team effectiveness.
• Demonstrated ability to drive innovation and share expertise across teams.

Responsibilities

• Support clinical trial start-up, activation, maintenance, and closeout, including timely collection and management of essential study documents.
• Maintain and quality-review trial information in CTMS, eTMF, and other clinical systems.
• Partner with internal teams, CROs, vendors, and investigative sites to support study execution and resolve operational issues.
• Support inspection and audit readiness through accurate, complete, and compliant trial documentation.
• Coordinate trial-related meetings, documentation reviews, approvals, and administrative activities.
• Manage purchase orders, invoices, investigator payments, and study-related financial tracking.
• Prepare, review, and quality-check study documents, reports, trackers, and investigator site files.
• Support TMF and ISF maintenance, reconciliation, and quality oversight.
• Coordinate training assignments, system access, and compliance tracking for study teams.
• Monitor site issues, action items, and data query resolution to support study milestones.
• Track and follow up on outstanding EDC queries and facilitate their timely resolution by study team members and/or sites.
• Facilitate site communications, including study updates, newsletters, and distribution of trial materials.
• Contribute to risk identification, issue escalation, process improvements, and inspection readiness efforts.
• Support development of SOPs, work instructions, guidance documents, and training materials.
• May assist with remote and on-site monitoring activities, as appropriate.

Benefits

• Health, dental, and vision insurance at competitive rates.
• Four weeks of vacation granted up front each year, prorated for the first and last year of employment.
• 12 company-paid holidays.
• Seven days of sick time.
• Employer-paid life insurance equal to 1x annual salary, up to $100,000.
• Employer-paid short- and long-term disability coverage.
• 401(k) with immediate eligibility and company matching contributions.
• Partially paid parental leave for eligible employees.
• Optional employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, identity theft protection, and pet insurance.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior