Scientist (Facility Director)

University of Miami•Coral Gables, FL

About The Position

The Frost Institute for Chemistry and Molecular Science seeks an outstanding Scientist (Facility Director) for the University of Miami’s Center for Mass Spectrometry. The Center enables research in proteomics, metabolomics, lipidomics, and mass measurements, including analysis of post-translational modifications and phosphorylation, megadalton macromolecular complexes, ligand, cofactor, lipid, and drug binding, macromolecular dynamics via hydrogen-deuterium exchange, and proximity relationships via crosslinking. Critical thinking skills for troubleshooting experimental challenges and interpreting complex data are essential. The Scientist supports the University’s research goals through complex experiments and investigations, contributes to the scientific community, and promotes the University’s reputation as a leader in the field. The Facility Director leads the daily operations and scientific strategy of the mass spectrometry core, maintains advanced instrumentation, provides analytical services, and partners with investigators on experimental design, sample preparation, protocols, and data analysis. The role also oversees and trains research personnel, students, postdoctoral fellows, and faculty, and contributes to manuscripts and grant applications. The University of Miami is a research institution and academic health system with more than 20,000 faculty and staff. It describes its culture as one where individuals are valued and empowered, and its community is united by purpose, collaboration, and service. The University is an Equal Opportunity Employer.

Requirements

  • Ph.D. in Chemistry, Biochemistry, or Molecular Biology.
  • Minimum 10 years of relevant experience.
  • Extensive hands-on experience operating high-resolution mass spectrometers, including the Thermo Fisher Orbitrap Ascend Tribid, Orbitrap Exploris 480 for Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS), and Q Exactive UHMR Hybrid.
  • Proven track record of managing a shared resource or research laboratory setting.
  • Skill in collecting, organizing, and analyzing data.
  • Ability to recognize, analyze, and solve a variety of problems.
  • Ability to exercise sound judgment in making critical decisions.
  • Expertise in biochemical sample processing, quantitative proteomics workflows (e.g., TMT, DIA, DDA, PRM, HDX-MS), and mass spectrometry data analysis software.
  • An appropriate combination of relevant education and experience may be considered.

Responsibilities

  • Oversee research employees, students, and other relevant staff.
  • Author scientific publications, technical and agency reports, and patent applications.
  • Assist in developing training materials for research staff.
  • Plan experiments and record and analyze findings.
  • Prepare research proposals and funding applications.
  • Ensure activities comply with applicable quality and regulatory standards.
  • Maintain current knowledge of relevant scientific and technical developments.
  • Present ongoing work and findings to colleagues at academic conferences.
  • Direct the daily operations of the mass spectrometry core facility and provide high-end technical leadership.
  • Maintain cutting-edge instrumentation, lead scientific strategy, and provide advanced analytical services for chemistry and molecular biology research.
  • Partner with investigators on mass spectrometry experimental design, sample preparation, protocols, and data analysis.
  • Coordinate with ThermoFisher engineers to maximize instrument uptime.
  • Perform routine instrument maintenance, including calibration and troubleshooting of high-resolution mass spectrometers and liquid chromatography systems.
  • Maintain sample processing records, scheduling, and usage logs for reporting and billing.
  • Participate in writing research manuscripts and grant applications.
  • Direct the training and instruction of students, postdoctoral fellows, and faculty members.
  • Adhere to University and unit-level policies and procedures and safeguard University assets.
  • Perform other duties or responsibilities as necessary.
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