FL114: Scientist, Genomics

Flagship Pioneering•Cambridge, MA

About The Position

FL114, Inc. is seeking an NGS-focused molecular biologist to join its Genomics team and contribute to the development and advancement of epigenetic editing programs, from early discovery research through preclinical development and beyond. The Scientist will work as an essential member of a close-knit, cross-functional team of experimental and computational scientists in a fast-paced, entrepreneurial environment. The role emphasizes experimental execution, technical depth, and direct bench work to help develop novel medicines.

Requirements

PhD in Molecular Biology, Genomics, or a related field, or a BS/MS with 7+ years of relevant NGS experience.
Direct experience performing NGS library preparation for Illumina platforms.
Familiarity with ATAC-seq, RNA-seq, ChIP-seq, Methyl-Seq, and/or 10X Single-cell.
Familiarity with Illumina instrumentation, liquid handlers, and Kingfisher automation.
Deep theoretical and applied knowledge of core molecular biology tenets.
Demonstrated experience developing, troubleshooting, and optimizing assays and protocols.
Enthusiasm, attention to detail, adaptability, motivation, and comfort working on a fast-paced, cross-functional scientific team.

Nice To Haves

Experience in an industrial, drug-development environment.
Immunology-related experience.

Responsibilities

Execute NGS-based functional genomics assays in a high-throughput production environment to address R&D needs in cell state mapping and therapeutic molecular validation.
Own the development and optimization of fit-for-purpose NGS solutions and molecular and cellular assay technologies.
Contribute directly at the bench as part of a small team, with a focus on technical depth.