Principal Scientist, Translational Immunology & Antibody Discovery Innovation

MSD•South San Francisco, CA
•$176,200 - $277,300

About The Position

The Principal Scientist will join the Discovery Biologics group in South San Francisco and contribute expertise in adaptive immunity and B-cell biology to advance immunization-based antibody discovery capabilities. The scientist will work with colleagues and groups across the organization to manage, perform, and troubleshoot antibody discovery programs. The role leads technology development initiatives for immunization-based de novo antibody discovery, with the aim of improving candidate hit quality and reducing timelines. It also involves leadership and participation in cross-functional discovery teams in partnership with therapeutic area scientists, fostering an inclusive, collaborative, high-performance culture, monitoring external scientific and technology advances, and promoting the external reputation of the Discovery Biologics department.

Requirements

  • Ph.D. in biophysics, biochemistry, structural biology, or a related science discipline, with 8 or more years of experience and relevant industry experience.
  • Expertise in vaccine discovery and therapeutic development.
  • Depth of knowledge in adaptive immunity and B-cell biology.
  • Track record of driving scientific and platform innovations in vaccine discovery and development.
  • Experience leading therapeutic vaccine discovery programs.
  • Established external reputation through publications, presentations, and/or scientific community engagement.
  • Excellent communication and collaboration skills.
  • Ability to manage multiple projects simultaneously.

Nice To Haves

  • Experience utilizing AI/ML to support discovery strategy initiatives.

Responsibilities

  • Propose and lead technology development initiatives for immunization-based de novo antibody discovery to increase candidate hit quality and decrease timelines.
  • Lead and participate in cross-functional discovery project teams in partnership with therapeutic area scientists.
  • Foster a high-performance growth mindset culture of collaboration, engagement, self-accountability, and inclusion.
  • Stay abreast of external advancements in relevant scientific and technology fields.
  • Promote the external reputation of the company’s Discovery Biologics department.
  • Help manage, perform, and troubleshoot antibody discovery programs.

Benefits

  • Medical, dental, and vision healthcare benefits and other insurance benefits for employees and families.
  • Retirement benefits, including 401(k).
  • Paid holidays, vacation, compassionate days, and sick days.
  • Annual bonus and long-term incentive, if applicable.
  • Relocation assistance is available domestically or internationally.

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What This Job Offers

Job Type

Full-time

Career Level

Principal

Education Level

Ph.D. or professional degree

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