Principal Engineer, Microsoft 365 and Copilot Platforms

Vertex Inc. • Boston, MA

2d • $144,000 - $216,000 • Hybrid

About The Position

The Principal Engineer, Microsoft 365 and Copilot Platforms is the execution-focused technical lead for Microsoft 365 Modern Work and enterprise AI capabilities, translating business demand into secure, governed, supportable outcomes. The role provides technical leadership across Microsoft Teams, SharePoint Online, OneDrive, and Exchange, with deep specialization in Microsoft Copilot, GitHub Copilot, Copilot Studio, agents, and AI governance. The work is approximately 60% hands-on and 40% technical leadership.

The role leads technical delivery for Modern Work and AI initiatives, including design, change control, implementation, and coordination with operations. It leads business escalations, critical incident management, root-cause analysis, and troubleshooting; enables Copilot and AI capabilities; and drives automation and continuous improvement. As the team’s technical authority, the engineer challenges solution designs, coordinates working sessions, engages business stakeholders, and documents supported technologies through environment documentation, SOPs, and knowledge-base articles.

Vertex is a global biotechnology company that invests in scientific innovation. The position is hybrid-eligible or on-site eligible. Employees in the hybrid designation may work remotely up to two days per week; the on-site designation involves five days per week on-site, with ad hoc flexibility. The role offers a stated base salary range of $144,000–$216,000 and is eligible for annual bonus and annual equity awards.

Requirements

• Principal- or Lead-level knowledge of Microsoft Teams, SharePoint Online, OneDrive, Exchange, Microsoft 365 governance, and related Entra ID, security, and compliance dependencies.
• Deep practical knowledge of Microsoft Copilot, Copilot Studio, Power Automate, Power Apps, agents, AI governance, and enterprise adoption controls, including Agent 365.
• Demonstrated ability to translate broad objectives and business requirements into secure technical designs and completed delivery outcomes.
• Ability to balance business enablement, user experience, and operational sustainability in a regulated enterprise environment.
• Experience leading complex technical escalations and coordinating execution across internal teams, control functions, vendors, and managed service providers.
• Excellent written and verbal communication skills, including explaining technical decisions, risks, and recommendations to technical and non-technical audiences.
• Strong analytical and problem-solving skills, with ability to work through ambiguity, incomplete information, shifting priorities, and multiple dependencies.
• Bachelor’s degree or equivalent degree in Information Systems, Computer Science, Engineering, Business, or a related discipline, or equivalent professional experience.
• Extensive experience delivering and governing enterprise Microsoft 365 Modern Work capabilities, including ownership of complex technical delivery, operational escalations, and cross-functional implementation.

Nice To Haves

• Experience implementing Microsoft Copilot, Copilot Studio, enterprise agents, AI governance, or related AI productivity capabilities.
• Experience working in a regulated enterprise environment and partnering with security, privacy, legal, compliance, identity, and operational teams.

Responsibilities

• Lead technical delivery for Modern Work and AI initiatives, including technical design, change control, implementation, and coordination with the operations team.
• Lead business escalations, critical incident management, root-cause analysis, and troubleshooting.
• Lead Microsoft Copilot and AI enablement, including Copilot SharePoint agents and Cowork, Copilot Studio, Power Automate, Power Apps, GitHub, and GitHub Copilot.
• Drive automation and continuous improvement across platforms.
• Serve as the team’s technical authority by challenging solution designs, coordinating working sessions, engaging business stakeholders, and driving solutions.
• Create and maintain environment documentation, standard operating procedures, and knowledge-base articles for supported technologies.

Benefits

• Annual bonus eligibility
• Annual equity awards
• Medical, dental, and vision benefits
• Generous paid time off, including a week-long company shutdown in the summer and winter
• Educational assistance programs, including student loan repayment
• Commuting subsidy
• Matching charitable donations
• 401(k)
• Other benefits and resources supporting employees’ career, financial, family, and wellbeing needs

What This Job Offers

• Job Type: Full-time
• Career Level: Principal