Principal Clinical Pharmacologist

Regeneron Pharmaceuticals • Warren, MI

5d • Onsite

About The Position

Regeneron is seeking a Principal Scientist, Clinical Pharmacology for its Pharmacometrics (PMx) group. The role sits within Clinical Pharmacology in the General Medicine group and reports to the Senior Group Director (SGD). The successful candidate will represent Clinical Pharmacology on project teams, providing strategic and scientific expertise for new and ongoing General Medicine clinical programs. They will make significant PMx contributions across multiple programs and help shape longer-term development strategies involving nonclinical experiments, clinical studies, and PMx analyses. The role includes conducting or overseeing development of PMx analysis plans.

The position is based in Tarrytown, New York; Warren, New Jersey; or Cambridge, Massachusetts, and requires working on site four days per week. The annual salary range is $150,500 to $245,500. Regeneron describes its total rewards package as potentially including annual bonuses or other incentive plans, equity awards, pension or retirement benefits, a 401(k) company match, health and wellness programs, fitness centers, medical, dental, vision, life, and disability insurance, paid time off, and family support benefits. The applicable package may vary by country and role.

Requirements

• PhD in a field such as Pharmacometrics, Biology, Pharmacology, or Engineering; or a PharmD or MD.
• At least 6 years of experience in clinical pharmacology.
• Strong communication skills to engage cross-functionally with colleagues at all levels of the organization.
• Innovative and flexible mindset, keen scientific interest, and a solid science background.

Responsibilities

• Develop and maintain comprehensive strategic Clinical Pharmacology development plans for assigned programs, with Senior Group Director supervision.
• Provide Clinical Pharmacology subject matter expertise and presentations to Clinical Study Teams, Development Teams, and senior management or governance meetings, with Senior Group Director supervision.
• Collaborate with and assist the Pre-clinical PK/PD Team and research teams to characterize preclinical PK/PD and predict human PK/PD, supporting clinical studies and business goals.
• Assist in drafting and finalizing clinical study protocols and study analysis plans, and draft, finalize, or review clinical pharmacology reports.
• Collaborate with the Medical Writing Team to incorporate PK/PD sections into clinical study reports.
• Provide Clinical Pharmacology support for regulatory documents, communications, and presentations, including INDs, health authority queries, BLA summary sections, and review inquiries, with Senior Group Director supervision.
• Represent Clinical Pharmacology at pre-IND, Type C, preBLA, and other health authority meetings, with Senior Group Director supervision.
• Work with Quantitative Pharmacology to develop quantitative strategies and deliver analyses and technical reports supporting strategic development plans.
• Actively publish work in scientific literature.
• Conduct or oversee the development of PMx analysis plans.

Benefits

• Competitive and comprehensive total rewards package, which may include annual bonuses or other incentive plans.
• Equity awards.
• Pension or retirement benefits.
• 401(k) company match.
• Health and wellness programs.
• Fitness centers.
• Medical, dental, vision, life, and disability insurance benefits.
• Paid time off.
• Family support benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree