Postdoctoral Associate | Sickle Cell Disease | Agoro Lab

The Jackson Laboratory • Bar Harbor, ME

7d • Onsite

About The Position

The Agoro lab at the Jackson Laboratory for Mammalian Genetics is seeking a highly motivated postdoctoral fellow to identify mechanisms that trigger sickle cell disease crisis. The goal of our laboratory is to determine the mechanisms of disease severity heterogeneity using systems biology. We use a multidisciplinary approach that integrates genetics, genomics, proteomics, and metabolomics to isolate systemic and tissue-specific marker of disease progression.

As a postdoctoral scientist in our lab, you will pioneer the development of new mouse models that recapitulate disease phenotypic heterogeneity as seen in patients. You will work with data generated from sickle cell disease patients. In our group, you will apply a broad range of cutting-edge technologies, including CRISPR-based tools, single-cell multi-omics, and create new disease mouse models that better recapitulate disease phenotype.
The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its research excellence, unparalleled mouse resources, state of the art facilities for computational science, mass spectrometry, imaging science, genome technologies, outstanding training environment characterized by scientific collaborations, and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.

Requirements

• Ph.D. in cell biology, molecular biology, genetics, or related field of study.
• Strong training background in molecular biology, cell biology, next-generation sequencing technology.
• Candidates should have at least one 1st author publication record in peer-reviewed journal.
• Excellent writing and communication skills, able to work independently and effectively with other members in a productive team.

Nice To Haves

• Experience in computational biology, genetic screens and single-cell technologies are particularly preferred.
• Show early independence through the JAX Scholars Program.

Responsibilities

• Pioneer the development of new mouse models that recapitulate disease phenotypic heterogeneity as seen in patients.
• Work with data generated from sickle cell disease patients.
• Apply a broad range of cutting-edge technologies, including CRISPR-based tools, single-cell multi-omics, and create new disease mouse models that better recapitulate disease phenotype.
• Expand professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management.

Benefits

• The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree