Post Doc

Jefferson Health PlansPhiladelphia, PA
Onsite

About The Position

A computational biologist position is immediately available in the laboratory of Dr. Fadia Ibrahim in the Department of Biochemistry and Molecular Biology, at Thomas Jefferson University. Our research program is focused on studying the molecular mechanism of a novel co-translational RNA decay process "ribothrypsis” and investigating the role of RNA dysregulation in neurodegenerative diseases. Our research integrates molecular biology, biochemistry, innovative RNA sequencing technologies, and advanced computational approaches. We are seeking a highly motivated computational biologist to support ongoing research projects, develop and implement bioinformatics tools and pipelines, and oversee the processing, management, and analysis of next generation sequencing (NGS) data.

Requirements

  • Ph.D. in Computational Biology, Bioinformatics, Computational Sciences, or a related discipline.
  • Proficiency in R and Python and in working in Linux/Unix environments with commandline-based bioinformatics tools.
  • Experience analyzing and interpreting NGS data, including RNA-Seq and Ribo-Seq, with expertise in data evaluation and visualization (e.g., differential expression, ribosome occupancy, poly(A) tail analysis, and modifications detection).
  • Basic knowledge of molecular biology techniques and familiarity with biological data.
  • Knowledge of statistical methods and their applications to biological datasets.
  • Strong analytical, problem-solving, and quantitative skills, with the ability to collaborate effectively in a multidisciplinary team environment.
  • Publication track-record in relevant fields.

Nice To Haves

  • Familiarity with NGS platforms, including Illumina and Oxford Nanopore Technologies.
  • Demonstrated ability to integrate, mine, and analyze diverse large-scale biological datasets.
  • Experience with commonly used bioinformatics resources, tools, and databases, including ENCODE, UCSC Genome Browser, Ensembl, Bioconductor, and NCBI databases.
  • Experience managing computational servers and data storage and backup.
  • Ability to formulate and develop scientific hypotheses that support ongoing research.
  • Strong organizational, written, and verbal communication skills.

Responsibilities

  • Support ongoing research projects
  • Develop and implement bioinformatics tools and pipelines
  • Oversee the processing, management, and analysis of next generation sequencing (NGS) data

Benefits

  • Medical (including prescription)
  • Supplemental insurance
  • Dental
  • Vision
  • Life and AD&D insurance
  • Short- and long-term disability
  • Flexible spending accounts
  • Retirement plans
  • Tuition assistance
  • Voluntary benefits (group rates on insurance and discounts)
  • Tuition discounts at Thomas Jefferson University after one year of full time service or two years of part time service.

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What This Job Offers

Job Type

Full-time

Career Level

Entry Level

Education Level

Ph.D. or professional degree

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