Head of CE Enterprise Operations

Genentech • Los Angeles, CA

10d • $158,700 - $294,700

About The Position

The Head of Customer Engagement (CE) Enterprise Operations leads the operating system that enables CE to focus resources on its highest-priority initiatives, launches, Role-Based Orchestration (RBO) work, and field-sponsored commitments. The role oversees the Enterprise Operations organization and is accountable for intake, prioritization, sequencing, governance, launch readiness, initiative delivery, and executive visibility across the CE enterprise portfolio. It connects CE Leadership, field leaders, HEDs, enterprise partners, and cross-functional teams to ensure work has clear ownership, disciplined execution, transparent progress, and measurable outcomes.

The leader manages and develops the Launch Operations Manager, Portfolio Operations Manager, Enterprise Initiatives Manager, and Enterprise Operations Leads; establishes organization-wide roles, decision rights, standards, and ways of working; and builds the talent and capabilities needed to deliver complex enterprise work consistently. The role owns the CE enterprise portfolio and its intake, prioritization, sequencing, capacity, dependencies, and tradeoffs, and provides recommendations to CE Leadership on portfolio choices and resource allocation.

The position sets common standards for launch readiness, initiative governance, milestone management, outcome measurement, and escalation. It oversees launch planning and readiness, integrates RBO and field-sponsored work into portfolio planning and delivery, and ensures initiatives have clear sponsors, owners, milestones, measures, and decision paths. It also provides CE Leadership with consolidated portfolio visibility, owns governance and decision cadence—including materials for CELT decisions and escalations—and continually improves the Enterprise Operations model.

Requirements

• Bachelor's degree required.
• Minimum of 10–12 years of pharmaceutical, biotechnology, consulting, commercial, strategic, operational, and/or analytical experience.
• Significant operations, portfolio, program, or enterprise transformation experience, including leading and managing teams.
• Demonstrated experience leading within large, complex, matrixed organizations.
• Experience establishing governance, prioritization, portfolio management, and execution systems.
• Demonstrated ability to influence senior leaders and lead through others.
• Experience leading organizational change and building new capabilities.
• Ability and willingness to travel for internal and external business meetings.
• Systems thinking and ability to see interdependencies and solve for the whole.
• Strong enterprise prioritization and portfolio management judgment, business acumen, and ability to synthesize data, risks, dependencies, and capacity.
• Strategic thinking and ability to translate strategy into disciplined execution.
• Strong executive presence and ability to influence senior leaders.
• Ability to make tradeoffs and challenge work that is not sufficiently prioritized.
• Ability to connect field, enterprise, and cross-functional teams and lead through influence in a complex, matrixed environment.
• Ability to simplify complexity and create transparent decision processes.
• Strong drive for results with an enterprise and customer mindset.
• Exceptional people leadership, coaching, and talent development capabilities.

Nice To Haves

• Graduate-level degree, such as an MBA or advanced life sciences degree.
• Experience supporting large-scale commercial or field organizations.
• Experience with launch operations, portfolio management, resource allocation, RBO, or enterprise transformation.

Responsibilities

• Lead, coach, develop, and manage the Launch Operations Manager, Portfolio Operations Manager, Enterprise Initiatives Manager, and Enterprise Operations Leads.
• Establish clear roles, decision rights, standards, and ways of working across Enterprise Operations.
• Build a community that shares tools, practices, insights, and capacity across workstreams.
• Create capabilities for consistently prioritizing, governing, and delivering complex enterprise work; recruit, develop, and retain high-performing talent.
• Own the enterprise portfolio of CE initiatives, launches, RBO work, and field-partner-sponsored commitments.
• Establish intake, evaluation, prioritization, and sequencing processes for proposed enterprise work.
• Maintain an integrated view of portfolio demand, dependencies, duplication, capacity constraints, and tradeoffs.
• Ensure resources are concentrated on high-value work aligned to CE strategy and business priorities; recommend portfolio choices, sequencing, and resource allocation to CE Leadership.
• Set common standards for launch readiness, initiative governance, milestone management, outcome measurement, and escalation.
• Oversee integrated launch planning, readiness assessments, risk escalation, and post-launch reviews across CE.
• Ensure selected enterprise initiatives have clear sponsors, owners, milestones, measures, and decision paths, and drive accountability for agreed priorities, milestones, and outcomes.
• Create an operating model for Regional leaders, HEDs, and other field partners to sponsor enterprise work without carrying the operational burden alone.
• Ensure field-sponsored priorities use the same transparent intake, prioritization, governance, and delivery system as other enterprise work.
• Oversee RBO operations support and integration with broader CE portfolio planning and execution.
• Connect enterprise work to the Regions, teams, field partners, and operational capabilities needed for delivery; identify recurring field needs suitable for enterprise-scale solutions.
• Provide CE Leadership with consolidated visibility into priorities, progress, risks, dependencies, and capacity.
• Own portfolio governance and decision cadence, including materials for CELT decisions and escalations; establish executive dashboards and outcome reviews.
• Identify opportunities to simplify governance, reduce duplication, and improve the speed and consistency of enterprise execution.
• Evolve the Enterprise Operations model based on business needs, field feedback, and execution lessons.
• Lead the development of a prioritized portfolio roadmap, integrated launch calendar and readiness view, portfolio governance cadence, capacity and tradeoff recommendations, executive dashboards, operating standards, and a talent and capability strategy.
• Travel for internal and external business meetings as needed.

Benefits

• A discretionary annual bonus may be available based on individual and Company performance.
• The position qualifies for company benefits, detailed at a link in the job posting; specific benefits are not listed.
• Relocation benefits are not available.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior