Director, Program Management

Crescent Biopharma•Waltham, MA
•$230,000 - $245,000

About The Position

The Director, Program Management will play a vital role on a high-performing cross-functional Program Team, facilitating and driving execution throughout the drug development lifecycle. In partnership with the Program Team Leader (PTL) and functional experts, the Director develops an integrated program plan supported by functional plans to deliver the program’s strategic objectives and drives team execution toward program goals. The role proposes and evaluates options that balance quality, speed, and cost; encourages robust discussion; and facilitates team decisions. Working with the PTL, the Director frames discussions to achieve alignment and data-driven decision-making, communicates program status and needs to the team and company leadership, and builds durable, trust-based relationships with stakeholders. The position calls for a solutions-oriented leader who can manage through influence and work effectively in a fast-paced, ambiguous environment. Crescent Biopharma is a clinical-stage oncology company developing therapies including a PD-1 x VEGF bispecific antibody and antibody-drug conjugates. The Director will maintain awareness of the evolving PD(L)-1/VEGF bispecific and ADC competitive landscape.

Requirements

  • Bachelor’s degree in science or a related field.
  • 10 or more years of relevant biotech or pharmaceutical industry experience in positions of increasing responsibility in drug development.
  • Proficiency with Microsoft Office programs (PowerPoint, Word, Excel, SharePoint, and Teams), Smartsheet, and other communication and project management tools.
  • Understanding of current and evolving artificial intelligence tool capabilities and limitations.
  • Strong analytical, strategic-thinking, and problem-solving skills.
  • Outstanding verbal and written communication skills, with the ability to communicate clearly, openly, consistently, and promptly in a transparent environment.
  • Experience building and maintaining program-level budgets and long-range plans.
  • Expertise in cross-functional teamwork and ability to influence all organizational levels without direct authority.
  • Ability to thrive in a fast-paced, ambiguous environment while managing competing priorities.
  • Sense of urgency and ability to prioritize multiple team deliverables and workstreams.
  • Results-driven approach and demonstrated experience working with highly effective teams.
  • Ability to lead effective discussions, invite productive discourse, and guide teams and organizations through complex, data-driven decisions.
  • Proven ability to establish and maintain trust-based relationships with team members and stakeholders.
  • Team-oriented approach that emphasizes collective achievement while maintaining individual responsibility and accountability for teamwork and product.
  • Commitment to fostering a diverse and inclusive workplace.

Nice To Haves

  • Advanced degree in a scientific discipline or an MBA.

Responsibilities

  • Lead operations of one or more cross-functional Program Teams, managing priorities, goal achievement, and resources while supporting a challenging, collaborative, and sustainable team environment.
  • Partner with the PTL to identify near-, mid-, and long-term priorities and propose paths forward, including facilitating strategic decisions.
  • Communicate program status, priorities, risks and mitigations, and needs clearly and openly to the Program Team, Crescent Senior Leadership, and other stakeholders.
  • Drive execution of the established program vision and strategy, emphasizing quality, speed, and cost.
  • Facilitate creation and maintenance of core program strategy documents, including the Target Product Profile (TPP), Clinical Development Plan (CDP), and Regulatory Strategy, in collaboration with cross-functional representatives and in alignment with the overall program strategy.
  • Support functional strategic and annual planning with current, fit-for-purpose materials for functional leaders and team representatives.
  • Create and maintain detailed cross-functional plans, integrated program plans, and visualizations.
  • Maintain up-to-date knowledge of the evolving PD(L)-1/VEGF bispecific and ADC competitive landscape.
  • Drive development and maintenance of the program-level budget and long-range plan in collaboration with Finance and the cross-functional team.
  • Provide alliance management support for the program, if applicable.

Benefits

  • Competitive compensation, including base salary, performance bonus, and equity.
  • 100% employer-paid benefits package.
  • Flexible PTO, including unlimited vacation PTO.
  • Two one-week company-wide shutdowns each year.
  • Professional development resources, mentorship, and growth opportunities.
  • Medical, dental, vision, life, and short- and long-term disability insurance.
  • 401(k) savings plan.
  • Long-term incentive program.
  • 10 sick days per calendar year.
  • Holiday pay, including two company shutdowns.
  • 16 weeks of parental leave within one year of the birth, adoption, or foster care of a child.
  • FMLA and military leave.
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