Director, Program Management

Prime Medicine•Cambridge, MA

About The Position

Prime Medicine is seeking an experienced program manager to lead program management for early research teams and strengthen the company’s program management methodology. The role focuses on advancing early discovery programs toward IND approval and reports to the Vice President, Programs and Strategy. Working with research leadership and cross-functional partners, the Director will guide program strategy and execution, manage integrated plans and budgets, support governance and decision-making, and communicate program progress. The role also contributes to long-range planning, portfolio prioritization, and continuous improvement of program management practices.

Requirements

  • Direct program management or program leadership experience for programs from discovery through early clinical development.
  • At least 6 years of industry experience, including at least 3 years managing programs.
  • Bachelor’s degree in a relevant scientific area.
  • Excellent verbal and written communication skills and strong interpersonal skills to manage relationships, set expectations, facilitate dialogue, and resolve conflict.
  • Ability to prioritize and drive complex programs to milestone completion.
  • Demonstrated proficiency in program management tools and methodology.
  • Strategic and financial acumen, including the ability to develop and manage program plans, budgets, and timelines.

Nice To Haves

  • Additional business training or education is strongly desired.
  • Experience in genetic medicines is highly desired.
  • Willingness to continually improve program management tools, implement best practices, and foster change management.

Responsibilities

  • Partner with research team leadership to develop and guide program strategy, set goals, and facilitate program decision-making.
  • Lead program management activities across programs, including project plans, timeline and milestone tracking, team meetings and minutes, and decision-making support.
  • Drive execution of program strategy and integrated development plans collaboratively and with urgency.
  • Identify risks, gaps, and resource bottlenecks, and develop and implement mitigation plans.
  • Develop and manage program budgets and long-range plans, including scenario planning; monitor program financials and resourcing plans.
  • Build strong working relationships across the organization to facilitate cross-functional communication.
  • Develop materials and present program updates and progress at internal company meetings.
  • Manage and communicate discovery-stage program plans.
  • Provide program progress input to the Leadership Team and facilitate cross-functional communication.
  • Support strategic scenario-planning discussions, develop risk and mitigation plans, and drive key program decisions through governance forums.
  • Reinforce high standards and high-performing teams to advance the company’s science.
  • Partner with Finance and Strategy/Portfolio Management on strategic and tactical program planning, long-range planning, investment planning, and portfolio prioritization.
  • Promote cross-functional and cross-program sharing of key learnings and drive change management as applicable.
  • Refine and reinforce Prime Medicine’s program management methodology and improve program management tools and practices.

Benefits

  • Annual short-term incentive award, such as a bonus.
  • Annual long-term incentive award, such as equity.
  • Medical insurance.
  • Dental insurance.
  • Vision insurance.
  • Life insurance.
  • 401(k) match.
  • Equity programs.
  • Generous paid time off.
  • Wellness days.
  • Company-wide recharge breaks.
  • Wellness benefits.
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