Director, Program Management

Celcuity

55d•$225,000 - $245,000

About The Position

The Director, Program Management is a strategic leader responsible for driving cross-functional planning, execution, and governance across one or more drug development programs. The role partners with Research, Clinical Development, Regulatory, CMC, Quality, and Executive Leadership to align program strategy, timelines, resources, risks, and milestones as programs advance from early-stage research through late-stage development and lifecycle management. The position requires a deep understanding of cross-functional biopharmaceutical development, exceptional leadership and communication skills, and the ability to influence across a matrixed organization to support timely, informed decision-making. The Director also champions operational excellence, mentors team members, and helps develop and scale Program Management capabilities. Celcuity is a commercial biotechnology company developing targeted therapies for solid tumor indications. Its first FDA-approved product is REVTORPYK (gedatolisib), and the company is conducting clinical trials evaluating gedatolisib in breast cancer and metastatic castration-resistant prostate cancer.

Requirements

PhD or bachelor's degree in Life Sciences, Biotechnology, or a related discipline.
At least 10 years of pharmaceutical or biotechnology industry experience, including significant experience leading cross-functional drug development programs.
Demonstrated experience supporting programs across multiple development stages, from early research through clinical development and lifecycle management.
Strong understanding of drug development, regulatory processes, and development governance.
Proven ability to influence, align, and lead diverse cross-functional teams in a matrix environment.
Exceptional communication, facilitation, organizational, and problem-solving skills.
Experience developing integrated project plans, managing risk, and driving strategic decision-making.

Nice To Haves

Advanced degree (MBA, MS, PhD, PharmD, or equivalent).
Oncology development experience.
Experience supporting major regulatory milestones, including INDs, CTAs, NDA/BLA submissions, and lifecycle management activities.
Experience managing alliances, CROs, CDMOs, and external development partners.
Prior experience within a scientific, clinical, regulatory, technical operations, or CMC function.
PMP or equivalent project management certification.
Experience with portfolio planning, resource management, and governance processes.

Responsibilities

Lead cross-functional development teams and drive execution of integrated program plans across stages of drug development.
Align development strategies with corporate objectives and portfolio priorities in partnership with program and functional leaders.
Develop and maintain integrated development plans, timelines, milestones, assumptions, and critical path analyses.
Monitor program progress and proactively identify risks, dependencies, and opportunities.
Facilitate program governance, stage-gate reviews, and executive decision-making.
Prepare executive dashboards, presentations, and recommendations on program status, risks, resource needs, and key decisions.
Advise senior leadership on program execution and portfolio considerations.
Promote accountability, alignment, and effective communication across functions and external partners.
Lead risk identification, mitigation planning, scenario analyses, and contingency planning.
Support resource planning, prioritization, and cross-functional capacity discussions.
Drive trade-off decisions balancing timelines, cost, quality, and business objectives.
Collaborate with Finance and functional leaders on program forecasting and budget planning.
Champion best practices, tools, and processes to improve program execution, transparency, and organizational effectiveness.
Drive continuous improvement initiatives that enhance collaboration and scalability.
Mentor team members and contribute to the development of Program Management capabilities.
Support strategic initiatives that strengthen and mature the Program Management function.