Clinical Program Manager

Intuitive•Sunnyvale, CA

About The Position

The Senior Clinical Program Manager serves as the strategic and operational partner to Clinical Development & Operations leadership, providing integrated program management across the Clinical Development & Operations portfolio from study startup through regulatory submission. The role partners with Clinical Development & Operations leadership to inform Clinical Development & Operations strategy through integrated planning, scenario analysis, governance, and execution insights, translating strategic direction into coordinated cross-functional plans that enable successful program execution. Reporting to the Program Management & Operations organization, the Senior Clinical Program Manager partners across Clinical Development & Operations, Regulatory Affairs, Medical Affairs, CMC, Nonclinical, Quality, Commercial, and external partners to integrate timelines, risks, dependencies, and key decisions into unified program plans. In partnership with Enterprise Program Management, the role establishes Clinical Development & Operations governance and ensures cross-functional risks, dependencies, and decision requests are appropriately elevated through enterprise governance to support informed decision-making and coordinated execution.

Requirements

Bachelor's degree in Pharma/Life Sciences, or a related field (or equivalent experience).
Minimum 10 years of program or project management experience in pharmaceutical, biotechnology, medical device, or CRO industry supporting Clinical Development & Operations through NDA regulatory submissions.
Demonstrated success leading cross-functional planning and execution across multiple concurrent clinical studies, including integrated planning, critical path management, and dependency management.
Experience partnering with Clinical Development & Operations, CMC, Regulatory Affairs, and Quality leadership to support governance, portfolio planning, and executive decision-making.
Experience supporting late-stage Clinical Development & Operations programs and familiarity with Clinical Development & Operations processes from start-up through close-out.
Expertise in integrated timeline management, risk and issue management, resource coordination, and cross-functional execution.
Strong executive communication and presentation skills, with the ability to deliver clear, actionable recommendations to senior leadership; High emotional intelligence and the ability to build trusted partnerships across technical and business functions.
Proficiency with Smartsheet, including integrated project planning, dashboards, reporting, and workflow automation.

Nice To Haves

An advanced degree is preferred.
Experience working with CROs, vendors, and cross-functional development teams
PMP or comparable project management certification.
Familiarity with procurement, contract, and financial management systems (e.g., Coupa, iValua, SAP, Ariba, or equivalent).

Responsibilities

Support the Program Management & Operations team in creating and implementing Clinical Development & Operations governance processes, including governance forums, operating cadences, decision pathways, program reporting, and the RAID framework.
Facilitate Clinical Development & Operations & Operations governance by preparing governance materials, maintaining clinical RAID and decision logs, capturing actions and decisions, monitoring follow-through, and escalating cross-functional risks and decision requests through enterprise governance, as appropriate.
Develop, maintain, and communicate integrated timelines across the clinical portfolio, ensuring alignment of milestones, dependencies, critical path activities, and cross-functional deliverables.
Coordinate program-level execution across Study Leads, Clinical Operations, Data Management, Biostatistics, Safety, Regulatory Affairs, Medical Writing, Quality, and external partners, providing hands-on project management support to individual studies as needed.
Monitor portfolio execution, proactively identifying schedule impacts, resource constraints, cross-study dependencies, and operational risks, and facilitate development of mitigation plans.
Develop executive-ready portfolio reporting that communicates program health, milestone performance, critical path status, key risks, decision requests, and recommended actions.
Identify portfolio trends and opportunities to strengthen planning, governance, reporting, and operational effectiveness across Clinical Development & Operations.
Support regular functional-area budget management in coordination with Clinical Development & Operations Functional Area Team Leads and PM&O by tracking actual and forecasted accruals, invoices, purchase orders, and inputs to the Annual Operations Budget Planning Cycle.
Support CRO and Vendor oversight by: incorporating vendor updates into project plans and governance materials; maintaining visibility and supporting management of purchase orders, change orders, invoices, key contract terms, and performance commitments; and coordinating business reviews and operational follow-up across internal functions.
Drive adoption of standardized project management tools, templates, dashboards, reporting practices, and workflow automation that improve portfolio visibility, consistency, and execution.