Hybrid Bench Scientist Automation Engineer

AstraZeneca•Cambridge, MA
•$116,284 - $174,426•Onsite

About The Position

AstraZeneca is seeking a skilled and motivated Scientist / Automation Engineer for its High Throughput Production & Screening (HTPS) biologics capability at its Kendall Square site in Cambridge, Massachusetts. The role combines hands-on laboratory science with laboratory automation to design, implement, optimize, and troubleshoot automated workflows. The successful candidate will help develop integrated end-to-end automation platforms supporting high-throughput expression, purification, and full characterization of antibody therapeutics at microgram-to-milligram scale. The position serves as an on-site scientific automation expert, partnering with a global automation team in Gaithersburg, Maryland, and Cambridge, UK. The role works with scientists, data engineers, and software developers to expand laboratory automation capabilities and improve throughput, precision, and scalability through robust, practical automated solutions. The position is based at AstraZeneca’s Kendall Square R&D site, a collaborative scientific and technical environment in Cambridge, Massachusetts. The annual base pay range is $116,284–$174,426, with eligibility for incentives including short-term incentive bonuses and equity-based awards for salaried roles. Benefits include qualified retirement programs, paid time off, and health, dental, and vision coverage, subject to applicable plan terms.

Requirements

  • Bachelor’s degree with 5 or more years of relevant experience, master’s degree with 3 or more years of relevant experience, or PhD with relevant experience.
  • Relevant education in biochemistry, molecular biology, or a related scientific discipline; chemical or mechanical engineering or a related engineering discipline; or computer science or a related computational discipline.
  • Demonstrated experience in both bench-based laboratory science and laboratory automation.
  • Proven ability to create, modify, and troubleshoot complex scientific standalone robotic methods and integrated automation systems.
  • Hands-on experience with cloning, transfection, and transduction methods.
  • Advanced knowledge of Hamilton, TECAN, and PerkinElmer automation platforms.
  • Experience with plate readers and flow cytometers.
  • Experience with plate sealers/peelers and automated barcode readers.
  • Experience with Green Button Go, Cellario, and Momentum integration software.
  • Ability to understand scientific workflows and translate them into efficient, reliable, and scalable automated solutions.
  • Track record of consistently developing new skills and knowledge while strengthening existing capabilities.
  • Ability to work independently and identify opportunities for self-development.
  • Excellent verbal and written communication skills.

Nice To Haves

  • Experience contributing to a science-driven team.
  • Experience with Lynx, Biomek, EVOware, or WinPREP automation platforms.
  • Experience with Green Button Go, Momentum, or Cellario, or programming languages such as Python or C#.
  • Familiarity with bioprocess development and experience working as a bench scientist.
  • Experience in line management.
  • Experience working in a global team.

Responsibilities

  • Combine bench science and automation expertise to support experimental execution and automated laboratory process development.
  • Develop and optimize integrated end-to-end automation platforms.
  • Support high-throughput expression, purification, and characterization workflows for antibody therapeutics.
  • Serve as an on-site expert in scientific automation while partnering with global automation teams in Gaithersburg, Maryland, and Cambridge, UK.
  • Build and expand laboratory automation capabilities.
  • Guide the development of complex workflows and automate key laboratory processes.
  • Provide technical expertise within a global team of automation engineers.
  • Collaborate with scientists, data engineers, and software developers.
  • Enhance laboratory throughput, precision, and scalability through practical automated solutions.
  • Translate scientific workflows into robust, scalable automation approaches.

Benefits

  • Qualified retirement programs.
  • Paid time off, including vacation, holidays, and leaves.
  • Health coverage.
  • Dental coverage.
  • Vision coverage.
  • Eligibility for short-term incentive bonuses.
  • Eligibility for equity-based awards for salaried roles.
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