AI Biologist - Rare and Progressive Disease

LatchBio•San Francisco, CA
•$140,000 - $180,000•Remote

About The Position

Latch builds rigorous scientific benchmarks for AI agents across biology and works with frontier labs and pharmaceutical companies to evaluate agents on real biological workflows. This early-team role focuses on rare and progressive diseases, excluding cancer, which is covered by a separate role. The successful candidate will help define strategy across multiple benchmarks. The role contributes to the technical approach for evaluating how AI agents can support diagnosis, treatment, research, and target discovery in rare and progressive disease. Working with scientists, physician-scientists, software engineers, and computational biologists, you will build ground-truth benchmark datasets from studies, your own experience, and novel work. These datasets will rigorously test whether agents can perform the analytical and interpretative steps expected of expert scientists.

Requirements

  • Advanced degree (MS, MD, PhD, or PharmD) in biology, genetics, physiology, computational biology, or a related biomedical field.
  • At least 3 years of hands-on research experience in relevant domains, with impact demonstrated through publications or industry experience.
  • Proficiency in Python and/or R for biological data analysis and visualization, or expert-level experience in experimental or methods design.
  • Deep scientific or clinical expertise in at least one relevant disease area, including rare genetic, autoimmune, infectious, or idiopathic diseases; neurodegeneration; or chronic progressive conditions such as COPD or MASH.
  • Expertise in designing and troubleshooting relevant wet- or dry-lab experiments, or expertise in clinical diagnosis, treatment, and research.

Nice To Haves

  • Strong existing opinions on where AI agents and LLMs fail in science or clinical practice.
  • Experience using agentic coding systems.

Responsibilities

  • Help define strategy across multiple scientific benchmarks.
  • Contribute to the technical approach for evaluating AI agents in diagnosis, treatment, research, and target discovery for rare and progressive diseases.
  • Build ground-truth benchmark datasets drawn from studies, professional experience, and novel work.
  • Design benchmarks that test whether AI agents can perform critical analytical and interpretative steps carried out by expert scientists.

Benefits

  • Health, dental, and vision coverage fully paid for the employee and 50% paid for dependents in the US.
  • 401(k) plan with no match.
  • 12 days of PTO to start, with more as you are promoted.
  • Company outings most months and team off-sites.
  • Catered lunch and dinner and unlimited snacks at the San Francisco office.
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