AI Biologist - Immunology
About The Position
Latch builds scientific benchmarks for AI agents across biology and works with frontier labs and pharmaceutical companies to evaluate agents on real biological workflows. The AI Biologist will join the Immunology team and serve as a scientific authority on ground truth, evaluating whether AI agents reason accurately about immune biology and vaccine development. The role involves working with scientists and engineers to build benchmark tasks and datasets, and setting standards for defensible agent outputs. The role translates immunology workflows into tasks with clear answers, writes gold-standard responses from raw data while accounting for donor, assay, and gating variability, and curates datasets spanning flow and spectral cytometry, single-cell and CITE-seq, TCR/BCR repertoires, cytokine panels, serology and neutralization titers, and ELISpot. The AI Biologist tests agents’ ability to distinguish biological findings from artifacts and to make nuanced interpretations, evaluates conclusions against expert standards, identifies reasoning failures and relevant evidence, and rewards appropriately expressed uncertainty. The position is full-time for US-based employees and contractor-based outside the US. Fully remote work is acceptable, though onsite work is preferred at Latch’s Mission Bay waterfront office in San Francisco. The company describes opportunities to advance through individual-contributor levels or move into pod management after a first promotion.
Requirements
- PhD in immunology, vaccinology, or a related field.
- Deep expertise in at least one of vaccine development, T/B cell or innate immune biology, autoimmunity, cancer immunology, inflammation, or immune cell engineering, demonstrated through peer-reviewed work or industry programs.
- Hands-on experience analyzing immune data using FlowJo, R, Python, or similar tools; programming is not required.
- Experience using Claude, ChatGPT, or similar AI tools, with the judgment to identify answers that are technically correct but scientifically wrong.
- Confidence in domain expertise to overrule an AI agent, combined with openness to updating conclusions when shown to be wrong.
Nice To Haves
- Industry experience.
Responsibilities
- Turn real immunology workflows into benchmark tasks with clear answers, covering immune profiling, vaccine immunogenicity, T and B cell responses, inflammation and autoimmunity readouts, and immune cell engineering.
- Write gold-standard answers from raw data with tolerances that reflect donor, assay, and gating variability.
- Curate data including flow and spectral cytometry, single-cell and CITE-seq, TCR/BCR repertoires, cytokine panels, serology and neutralization titers, and ELISpot.
- Test whether AI agents can distinguish real biology from artifacts such as doublets, spillover populations, batch effects, and sampling-depth effects.
- Test whether agents distinguish immunogenicity from protection, activation from exhaustion, and mouse findings from human relevance.
- Evaluate agent conclusions against expert standards and challenge answers that would not withstand expert review.
- Identify where agents go wrong, what an expert would do instead, and what evidence would change an assessment.
- Reward explicit uncertainty rather than confident guesses.
Benefits
- US employees receive health, dental, and vision coverage, 100% covered for the employee and 50% covered for dependents.
- 401(k) plan with no match.
- 12 days of PTO to start, with more as employees are promoted.
- The first four weeks are paid at full OTE during training.
- Full OTE is paid when quota cannot fairly apply, such as when a new project is starting, the platform is down, or the employee is assigned to a special project.
- H-1B sponsorship for new petitions and transfers, O-1 and TN sponsorship, and STEM OPT support.
- Company outings most months and team off-sites.
- Onsite office amenities include catered lunch and dinner and unlimited snacks.
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
