Medicinal Chemist Jobs

About The Position

Requirements

• Master’s degree in Chemistry, Medicinal Chemistry, Biochemistry, or a related chemistry discipline, and 4 years of academic or employment experience with synthetic organic chemistry or medicinal chemistry.
• OR PhD in Chemistry, Medicinal Chemistry, Biochemistry, or a related chemistry discipline, and 1 year of academic or employment experience with synthetic organic chemistry or medicinal chemistry.
• Minimum of 1 year of experience supporting drug discovery at the molecular design stage.
• Minimum of 1 year of experience with improving in vitro and in vivo potency, selectivity, and ADMET properties.
• Minimum of 1 year of experience with new modalities including targeted protein degradations, siRNA, ADCs, and oral peptides.

Responsibilities

• Formulate hypotheses, and design and synthesize novel small molecules.
• Optimize lead compounds to improve potency, selectivity, physicochemical properties, and ADMET to meet the target product profiles required to invent high-quality medicines.
• Collaborate with external CRO chemistry resources to implement design ideas and optimize chemistry productivity.
• Direct fast-paced SAR iterations through proposal and execution of synthetic routines.
• Maintain a strong safety culture.
• Partner cross-functionality to address specific program needs, increase overall organization, and provide Medicinal Chemistry perspectives.

Benefits

• company bonus (depending, in part, on company and individual performance)
• company-sponsored 401(k)
• pension
• vacation benefits
• medical, dental, vision and prescription drug benefits
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• life insurance and death benefits
• certain time off and leave of absence benefits
• well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)