Winter Co-op/Safety Pharmacology

GSK Internships & Co-ops powered by Atrium•Upper Providence, PA

11d•$22 - $43•Onsite

About The Position

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. The Safety Pharmacology group in Non-Clinical Safety, Pre-Clinical Sciences is a multi-site resource focused on the proactive management of pre-clinical safety concerns in the cardiovascular, respiratory, and CNS areas and their translation to man. Safety Pharmacology supports all therapeutic areas from idea to loss of exclusivity including experimental approaches to aid target and compound selection, regulatory pre-FIH safety studies and post-FIH investigative studies to address clinical findings and manage risk. The broad remit of the department requires strong discipline expertise and a clear and strong interface with the portfolio. This position is an exciting opportunity to make a difference in the lives of patients by applying human physiology and pharmacology expertise coupled with translational knowledge and industry experience to drive drug discovery and development.

Requirements

Pursuing a Bachelor's, Master's or PhD degree Biology, Chemistry or similar discipline.
Must be able to work full-time (35-40 hours/week) throughout the duration of the 6-month assignment (January ~ July 2027).
Must have an active student status and/or within 12 months post-graduation from a BS or MS degree program.
Post-doctoral candidates are not eligible.
Must successfully pass a drug screen and background check prior to assignment target start date.

Nice To Haves

Basic understanding of biology, anatomy and physiology.
Successful completion of at least one year of college level courses.
Majors in the biology, pharmacology, physiology or toxicology are preferred.
Hands on experience of cell culture, basic microscopy, patch-clamp electrophysiology, is preferred.

Responsibilities

Assist in conduct of in vitro Safety Pharmacology (SP) CNS & CV studies including culturing of transformed cell lines and human inducible pluripotent stem cells, recording of membrane excitability using multi-electrode array platforms, cellular electrophysiology and ion channel pharmacology.
Conduct reagent and buffer preparation, formulation of drug solutions, contribute to study related documentations from notebook setup to data analysis and processing.
Assist senior scientists in conduct of experiments.
Assist in setting up, operating & maintaining specialized equipment & apparatus (multi-electrode array, automation platform, pipettes, path-clamp electrophysiology systems, microscopes) for evaluating in vitro CV and CNS function.
Cross-train with scientists within the group in SP & assist with CV & CNS ion channel pharmacology, in vitro & ex vivo cardiac physiology, cardiac myocyte excitation-contraction coupling & stem cell physiology, & in vitro seizure liability detection.