Staff Scientist

Guidehouse•Tysons Corner, VA

2d•Onsite

About The Position

We are currently searching for a Staff Scientist to provide laboratory leadership and support services to perform interdisciplinary and collaborative research from bench to beside with the National Heart, Lung, and Blood Institute (NHLBI). This is a full-time, on-site opportunity in Bethesda, MD. Combine biochemical, molecular, cellular, genetic, and quantitative approaches to investigate fundamental biological processes across a range of organisms, including fish, flies, mice, mammals, microbes, and viruses. Research how cells sense, respond, and adapt to a variety of stress conditions, including nutrient deprivation, organelle damage, and pathogen infection. Address how alterations in mTOR, TFEB, TFE3, and lysosomal function lead to human disease. Seek to identify potential sites for therapeutic intervention suitable for further evaluation in translational and clinical research efforts. Serve as laboratory lead contributing to training and mentoring of all laboratory members. Present research at meetings and conferences. Work in an interdisciplinary lab collaborating with others to advance research initiatives. Characterize the contribution of lysosomes to a variety of physiological processes, both in normal and pathological conditions.

Requirements

PhD with MINIMUM TWO (2) years of postdoctoral research experience in molecular biology, cellular biology, biochemistry, or related field.
Mastery of Zebrafish models with skills such as husbandry, genetic crossing, and genotyping protocols.
Strong publication record.
Experience working with animal models.
Expertise in cellular biology and advanced microscopy imaging.
Must be able to obtain and maintain a Federal or DoD Public Trust.
Candidates must receive approved adjudication of their Public Trust prior to onboarding with Guidehouse.

Nice To Haves

Knowledge of organelle cell biology (lysosomes, autophagy, intracellular trafficking), and a commitment to conducting related high-quality research.
Able to work independently and in a team setting.
Excellent oral and written communication abilities.
Outstanding interpersonal and time management skills.
Demonstrated experience in staff training and mentoring.
Candidates with an active Public Trust or existing suitability are preferred.

Responsibilities

Provide laboratory leadership and support services to perform interdisciplinary and collaborative research.
Combine biochemical, molecular, cellular, genetic, and quantitative approaches to investigate fundamental biological processes.
Research how cells sense, respond, and adapt to a variety of stress conditions.
Address how alterations in mTOR, TFEB, TFE3, and lysosomal function lead to human disease.
Identify potential sites for therapeutic intervention.
Serve as laboratory lead contributing to training and mentoring of all laboratory members.
Present research at meetings and conferences.
Work in an interdisciplinary lab collaborating with others to advance research initiatives.
Characterize the contribution of lysosomes to a variety of physiological processes, both in normal and pathological conditions.

Benefits

Medical, Rx, Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Parental Leave
401(k) Retirement Plan
Group Term Life and Travel Assistance
Voluntary Life and AD&D Insurance
Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
Transit and Parking Commuter Benefits
Short-Term & Long-Term Disability
Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
Employee Referral Program
Corporate Sponsored Events & Community Outreach
Care.com annual membership
Employee Assistance Program
Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)