Sr. Scientist - Systems Immunology

Amgen•Burnaby, BC

About The Position

Amgen’s Immunoengineering organization is seeking an experienced, enthusiastic, and collaborative Scientist to join the Experimental Immunology Team at our Amgen British Columbia site. This is a systems immunology-focused position involving the integration, analysis, and interpretation of high-dimensional immune profiling datasets to support discovery and translational research efforts. The ideal candidate will possess deep foundational expertise in immunology combined with strong computational and quantitative biology skills. This role will focus on the integration of multimodal datasets including high-dimensional spectral cytometry, secretomics, and transcriptomics to uncover immune mechanisms, characterize complex cellular phenotypes, and identify biomarkers and therapeutic hypotheses. The successful candidate will work closely within cross-functional research teams to design studies, develop analytical workflows, and generate biologically meaningful insights from complex datasets. Experience with systems-level analysis approaches, data visualization, statistical modeling, and multi-omics integration is highly desired. Well-suited applicants will demonstrate scientific creativity, intellectual curiosity, strong communication skills, and the ability to thrive in a collaborative, interdisciplinary environment. This individual will also have a track record of high-quality research, innovative problem-solving, and enthusiasm for addressing challenging questions in immunology and translational science.

Requirements

PhD in a related discipline with 2+ years of experience
MSc with 5+ years of experience
BSc with 8+ years of experience

Nice To Haves

Deep understanding of immunology with expertise in systems immunology approaches and quantitative data analysis.
Experience integrating and analyzing high-dimensional immune profiling datasets including spectral cytometry, secretomics, and transcriptomics.
Strong computational and statistical analysis skills with experience using bioinformatics tools and programming languages such as R and/or Python.
Experience with dimensionality reduction, clustering, and visualization approaches for high-dimensional datasets.
Experience working with multi-omics datasets and developing biologically meaningful interpretations from complex data.
Strong written and verbal communication and interpersonal skills.
Desire to be a team player in a dynamic, cross-functional environment.
Demonstrated scientific analysis and problem-solving skills.

Responsibilities

Integration, analysis, and interpretation of high-dimensional immune profiling datasets
Integration of multimodal datasets including high-dimensional spectral cytometry, secretomics, and transcriptomics
Uncover immune mechanisms
Characterize complex cellular phenotypes
Identify biomarkers and therapeutic hypotheses
Design studies
Develop analytical workflows
Generate biologically meaningful insights from complex datasets