Senior Scientist - Immunology Biology

Arcus Biosciences•Hayward, CA

3d•Onsite

About The Position

The Biology department is seeking a self-motivated, knowledgeable, and technically skilled immunologist with a deep understanding of inflammatory and autoimmune disease mechanisms. In this role, you will design, execute, and interpret experimental studies to demonstrate the mechanism of action for small-molecule and biologic therapies. Senior scientists operate in a highly collaborative environment, working closely with colleagues across the organization to enable the progression of novel drug candidates from discovery into the clinic.

Requirements

PhD in immunology or a related scientific discipline with 3+ years of relevant industry experience
Deep understanding of inflammatory and autoimmune disease mechanisms demonstrated through scientific presentations and publications
Strong ability to identify, design, and fully analyze critical experiments, develop experimental next steps, and integrate new information to revise previous hypotheses
Extensive expertise in the isolation, culture, and functional evaluation of primary immune cells (mouse and human)
Proficiency with immunoassay techniques including multi-color flow cytometry, ELISA (or equivalent method) and western blot
Demonstrated expertise in the design and execution of murine models of inflammation including study design, tissue collection/processing, and ex vivo immunophenotyping to support the mechanism of action for drug candidates
Strong collaboration and leadership skills—including cross-functional teamwork, clear presentations, and mentoring of junior scientists
Well-developed scientific communication skills with demonstrated experience preparing external scientific materials including conference abstracts, scientific posters, and manuscripts for peer‑reviewed publication

Responsibilities

Lead elements of drug discovery programs by providing scientific insight, generating robust experimental data packages, and developing mechanistic models of disease to advance Arcus drug candidates.
Mentor junior scientists through hands-on training, technical guidance, and feedback in experimental design, troubleshooting, and data interpretation.
Design, execution, and optimization of in vitro and in vivo model systems to support therapeutic hypotheses and confirm the mechanism of action for candidate molecules.
Contribute both intellectually and experimentally within a multidisciplinary team to regularly synthesize, interpret, and present results in internal forums and, as appropriate, external scientific venues.