Scientist - Molecular Immunology

Amgen•Burnaby, BC

1d•Onsite

About The Position

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist – Molecular Immunology What you will do Let’s do this. Let’s change the world. Amgen’s Immunoengineering organization is seeking an experienced, enthusiastic, and collaborative Scientist to join the Experimental Immunology Team at our Amgen British Columbia site. This is a laboratory-focused position involving the design, development, and execution of molecular and cellular biology research platforms to support immunology and therapeutic discovery programs. The ideal candidate will possess a strong foundation in molecular biology and protein biochemistry combined with broad hands-on technical expertise across multiple experimental systems and technologies. This role will contribute directly to the development of novel technologies, molecular tools, and next-generation research platforms within a highly collaborative and fast-paced research environment. The successful candidate will have experience spanning protein engineering and characterization, bio-conjugation strategies, and molecular construct design. The position will involve work with protein expression systems, engineered fusion proteins, and molecular tagging approaches including SNAP/CLIP technologies, as well as analytical characterization techniques such as Western blotting, HPLC, and mass spectrometry. Experience designing and generating lentiviral, AAV, and plasmid-based systems is highly desired, along with expertise in primary cell culture and cellular assay development. Additional experience working with RNA biology, RNA-protein immune complexes, and related molecular interrogation techniques will be valuable for success in this role. Well-suited applicants will demonstrate scientific curiosity, adaptability, and enthusiasm for learning and applying a wide range of experimental approaches. We are particularly interested in candidates with a broad and versatile technical skill set who are excited to work across disciplines and contribute to the development of innovative experimental capabilities and enabling technologies. This individual will thrive in a team-oriented environment and will bring strong experimental rigor, creativity, and problem-solving skills to challenging scientific questions. The candidate should also possess excellent communication skills and a demonstrated ability to work collaboratively across cross-functional research teams.

Requirements

PhD in a related discipline with 0-2 years of experience
MSc with 3-4 years of experience.
BSc with 5+ years of experience.
Strong foundation in molecular biology, protein biochemistry, and cellular biology.
Hands-on experience with protein design, engineering, expression, purification, and characterization workflows.
Experience with bio-conjugation strategies and engineered protein systems including fusion proteins and SNAP/CLIP tag technologies.
Experience using analytical and characterization techniques including Western blotting, HPLC, and mass spectrometry.
Experience designing and generating lentiviral, AAV, and plasmid-based expression systems.
Experience with primary cell culture and cell-based assay development.
Experience working with RNA biology and RNA/protein immune complexes.
Broad laboratory training with the flexibility and curiosity to work across multiple technology areas and experimental platforms.
Strong written and verbal communication and interpersonal skills.
Desire to be a team player in a dynamic, cross-functional environment.
Demonstrated scientific analysis and problem-solving skills.

Responsibilities

Design, development, and execution of molecular and cellular biology research platforms to support immunology and therapeutic discovery programs.
Contribute directly to the development of novel technologies, molecular tools, and next-generation research platforms.
Work with protein expression systems, engineered fusion proteins, and molecular tagging approaches including SNAP/CLIP technologies.
Utilize analytical characterization techniques such as Western blotting, HPLC, and mass spectrometry.
Design and generate lentiviral, AAV, and plasmid-based systems.
Develop primary cell culture and cellular assays.
Work with RNA biology, RNA-protein immune complexes, and related molecular interrogation techniques.
Demonstrate scientific curiosity, adaptability, and enthusiasm for learning and applying a wide range of experimental approaches.
Work across disciplines and contribute to the development of innovative experimental capabilities and enabling technologies.
Bring strong experimental rigor, creativity, and problem-solving skills to challenging scientific questions.
Possess excellent communication skills and a demonstrated ability to work collaboratively across cross-functional research teams.