Sr Assoc Scientist, Intact Mass (Analytical and Biological Mass Spectrometry)

Regeneron Pharmaceuticals • Tarrytown, GA

1d • $80,300 - $131,100 • Onsite

About The Position

Regeneron is seeking a highly motivated Sr. Associate Scientist to join the Intact Mass, proteomics technologies and key MS platforms team within the Analytical and Biological Mass Spectrometry (ABMS) Group. The role develops and applies LC-MS-based analytical methods to advance the company’s pipeline across development stages, including antibodies (monospecific, bispecific, and alternative formats), antibody-drug conjugates (ADCs), and emerging modalities such as AAVs and siRNA. It uses mass spectrometry and analytical technologies to characterize therapeutic candidates, with a focus on critical quality attributes and process development, in collaboration with cross-functional teams.

The position is full-time and on-site in Tarrytown, New York, in a fast-paced, collaborative R&D laboratory environment. The annual salary range is $80,300 to $131,100.

Requirements

• Master’s degree and at least 3 years of relevant experience, or a bachelor’s degree and at least 6 years of relevant experience, in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field.
• Industrial or academic experience in analytical characterization of protein therapeutics, bioconjugates, or other therapeutic modalities.
• Strong knowledge of and hands-on experience with LC-MS-based characterization of proteins, peptides, and antibody-drug conjugates, including sample preparation, liquid chromatography, mass spectrometry, and data analysis.
• Enjoy developing and troubleshooting analytical methods and solving complex scientific and technical problems.
• Strong cross-functional collaboration and communication skills, including the ability to build productive working relationships and coordinate work across multiple programs.

Nice To Haves

• Experience with advanced mass spectrometer platforms such as Orbitrap, Q-TOF, and triple quadrupole instruments.
• Experience with liquid chromatography and relevant data processing software, such as Xcalibur, Protein Metrics, ChemDraw, Skyline, and Proteome Discoverer.

Responsibilities

• Develop and apply LC-MS-based analytical methods to characterize monoclonal antibodies and other therapeutic protein candidates across R&D programs.
• Prepare samples, conduct LC-MS experiments, and analyze data using relevant software and bioinformatics tools to characterize product quality attributes.
• Document results in electronic laboratory notebook entries, presentations, and reports.
• Support process development, R&D activities, and regulatory submissions through analytical characterization and scientific problem-solving.
• Collaborate with cross-functional teams to understand analytical needs and coordinate samples, study activities, priorities, timelines, and deliverables.
• Interpret and communicate scientific results in project and group meetings, technical reports, regulatory documents, conferences, and peer-reviewed publications.
• Plan and prioritize work, manage and visualize data, and provide clear, timely updates.

Benefits

• Student Loan Paydown program and tuition reimbursement
• Family care benefits
• Relocation assistance
• Inclusion, culture, and well-being programs, including physical and mental health
• Potential annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits, paid time off, and family support benefits

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level