Scientist, Quantitative Bioanalytics - Analytical and Biological Mass Spectrometry (ABMS)
About The Position
Regeneron is seeking a highly motivated, collaborative Scientist to join the Quantitative Bioanalytics (QBA) team within the Analytical and Biological Mass Spectrometry (ABMS) Group. The role is based in a state-of-the-art mass spectrometry laboratory and focuses on developing, qualifying, validating, and applying LC-MS-based bioanalytical assays and other analytical methods to support R&D programs. The scientist will contribute to mass spectrometry technologies used in bioanalysis and biologics characterization across Regeneron’s therapeutic pipeline, working with cross-functional teams to understand analytical needs and coordinate samples, study activities, priorities, and timelines. The position supports research, preclinical, clinical, and biodistribution studies by quantifying therapeutics or biomarkers in biological samples. It involves increasing independence and project ownership, troubleshooting and optimizing analytical methods, ensuring data quality and scientific integrity, maintaining records, interpreting results, and communicating findings through team meetings, technical reports, regulatory documents, conferences, and publications. The role is full-time and on-site in Tarrytown, New York.
Requirements
- BS or MS in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field.
- At least 6 years of experience with an MS degree or 8 years with a BS degree in industrial or academic LC-MS-based bioanalytical assays for biomarkers, protein therapeutics, antibodies, AAVs, or other therapeutic modalities.
- Hands-on experience with LC-MS and advanced mass spectrometry platforms such as triple quadrupole, Q-TOF, and Orbitrap.
- Strong understanding of mass spectrometry techniques and their applications to large-molecule analysis.
- Excellent attention to detail, record-keeping, and organizational skills.
- Ability to work independently and collaboratively, communicate clearly and effectively in writing and verbally, and adapt to changing priorities.
Nice To Haves
- Experience in a GxP laboratory environment, documentation, and regulatory compliance in the biotech or biopharmaceutical industry.
- Deep understanding of analytical method qualification and validation.
- Knowledge of ELISA and other ligand-binding assays.
Responsibilities
- Develop, qualify, and validate LC-MS-based assays for biotherapeutics and biomarkers in biological matrices.
- Perform bioanalysis and support research, preclinical, clinical, and biodistribution studies by quantifying therapeutics or biomarkers in study samples.
- Apply LC-MS platforms, including triple quadrupole, Q-TOF, and Orbitrap instruments, with manual or automated sample preparation to investigate a range of biotherapeutics and modalities.
- Troubleshoot and optimize methods while ensuring data quality and scientific integrity of bioanalytical and biologics characterization results.
- Maintain accurate records, including electronic lab notebooks and other documentation; analyze and interpret results; and communicate findings in meetings, technical reports, regulatory documents, conferences, and peer-reviewed publications.
- Develop and troubleshoot analytical methods, solve scientific and technical problems, and explore new technologies and approaches to address bioanalytical challenges.
- Coordinate samples, activities, priorities, timelines, and deliverables across multiple programs and teams.
- Take increasing ownership of projects and priorities while working independently on well-defined projects and collaboratively across teams.
- Build productive working relationships and adapt to changing priorities in a fast-paced R&D environment.
Benefits
- Competitive and comprehensive total rewards package, depending on country and role.
- Annual bonuses or other incentive plans may be included.
- Equity awards may be included.
- Pension or retirement benefits may be included.
- 401(k) company match may be included.
- Health and wellness programs may be included.
- Fitness centers may be included.
- Medical, dental, vision, life, and disability insurance benefits may be included.
- Paid time off may be included.
- Family support benefits may be included.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
