Senior Systems Analyst, Data Operations

Amylyx Pharmaceuticals • Cambridge, MA

2h • $138,000 - $155,000 • Remote

About The Position

Amylyx Pharmaceuticals is seeking a highly motivated, hands-on Senior Systems Analyst, Data Operations to support and continuously improve its enterprise data and analytics ecosystem. The role maintains the day-to-day operation of critical data platforms, integrations, and reporting solutions serving Commercial, Medical, R&D, Quality, Finance, and Corporate functions. It is responsible for the reliability, accuracy, and efficiency of data pipelines, system integrations, master data processes, and reporting environments.

The position is the primary operational lead for data platform support, troubleshooting, incident resolution, and vendor coordination. It also partners with business stakeholders to identify enhancements and deliver new capabilities. The work is highly hands-on and requires technical expertise in Snowflake, Power BI, Talend/Qlik Data Integration, Python, SQL, APIs, and Master Data Management. The analyst works with managed service providers, implementation partners, internal IT teams, and business stakeholders to deliver high-quality, scalable data solutions.

The position may be performed remotely within the United States, but the employee must be able to attend meetings at the Cambridge, Massachusetts office regularly. Preference is given to candidates in New England who can attend in person as needed. Remote workers must have an appropriate private work setting, reliable internet, a phone, and the ability to video conference.

The estimated base salary range is $138,000–$155,000 USD. Eligible employees may also receive annual performance-based bonuses and equity awards. Amylyx offers a comprehensive benefits package intended to support employees’ health, well-being, and financial security.

Requirements

• Bachelor’s degree in Information Systems, Computer Science, Engineering, Business, or a related discipline.
• At least 5 years of experience supporting enterprise data platforms, data warehouses, analytics solutions, or data operations environments.
• Hands-on experience with Snowflake, SQL/SnowSQL, Python, Power BI, and Talend or Qlik Data Integration.
• Strong experience supporting production data operations and troubleshooting complex data issues.
• Hands-on experience with Master Data Management (MDM), reference data management, and data quality processes.
• Experience developing and supporting ETL/ELT pipelines and data integrations.
• Experience working with APIs, file-based integrations, and SaaS application integrations.
• Strong understanding of data warehousing, data modeling, data governance, data quality, and integration architecture.
• Experience gathering business requirements and converting them into technical solutions.
• Experience managing external vendors, consultants, or managed service providers.
• Strong problem-solving, analytical, and troubleshooting skills.
• Excellent communication skills with technical and non-technical audiences.
• Ability to attend meetings regularly at the Cambridge, Massachusetts office.
• For remote work, access to a work setting that supports privacy, reliable internet access, phone use, and video conferencing.

Nice To Haves

• Experience in biotechnology, pharmaceuticals, healthcare, or regulated industries.
• Experience supporting commercial pharmaceutical data environments.
• Experience supporting commercial data sources such as Specialty Pharmacy, Specialty Distributor, Claims Data, Patient Services, Formulary, and Market Access Data.
• Experience working in Agile delivery environments.
• Snowflake, Microsoft, Talend, Qlik, or Power BI certifications.
• Residence in the New England region and ability to attend in person as needed.

Responsibilities

• Monitor and support day-to-day operations of the enterprise data platform and analytics ecosystem.
• Ensure successful execution of data ingestion, transformation, integration, and reporting processes.
• Monitor scheduled jobs, data pipelines, interfaces, workflows, and report refreshes.
• Identify, troubleshoot, and resolve production issues affecting data availability, quality, or performance; perform root cause analysis and implement corrective and preventive actions.
• Coordinate incident resolution across internal teams and external support providers, and maintain operational dashboards, monitoring, alerting, and service metrics.
• Ensure adherence to service-level agreements and operational support processes.
• Develop, maintain, and support data integration processes and ELT/ETL workflows using Snowflake, Talend/Qlik Data Integration, Python, SQL, and APIs.
• Support ingestion from Veeva, Salesforce, NetSuite, HR systems, data vendors, and third-party SaaS platforms.
• Execute code reviews and ensure development standards are followed; optimize database performance, transformations, and reporting processes.
• Support environment migrations, deployments, testing, and release management.
• Support enterprise Master Data Management processes and solutions, including customer, product, organization, territory, and reference data maintenance.
• Monitor data quality metrics, investigate and resolve master data discrepancies and integration issues, and support data quality controls and standards.
• Collaborate with stakeholders to improve data governance and stewardship processes.
• Gather, document, and prioritize business requirements; facilitate workshops, requirements sessions, and process reviews.
• Translate business requirements into technical designs and implementation plans; evaluate enhancement, reporting, dashboard, integration, and automation requests.
• Coordinate development between internal teams and external implementation partners, and perform functional and technical testing.
• Ensure solutions are delivered on time, within scope, and to quality expectations; support user acceptance testing, training, and adoption.
• Support and maintain Power BI reporting solutions and semantic models; troubleshoot refresh failures, data discrepancies, and performance issues.
• Partner with business users to improve reporting capabilities and KPI delivery; develop or enhance dashboards and reports as needed, ensuring alignment with business requirements and data standards.
• Serve as the primary operational liaison for managed service providers and external partners; manage outsourced support and development activities.
• Track service performance, issue resolution, backlog, and deliverables; review technical deliverables for compliance with Amylyx standards and escalate issues and risks.
• Drive continuous improvement initiatives with vendors and support partners.

Benefits

• Eligible employees may receive annual performance-based bonuses.
• Eligible employees may receive equity awards.
• Comprehensive benefits package designed to support health, well-being, and financial security.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior